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3 492 (0,086s) •

Project

Characterization of telomer chromatin proteins (IAC5004111)

complexes of telomeres. The project is focused on characterization of previously detected 40 kDa telomere-binding protein, its purification and partial sequencing. Besides, characterization of telomeric c...

CE - Biochemie

  • 2001 - 2001
    • •
  • 344 tis. Kč
    • •
  • 207 tis. Kč
    • •
  • AV ČR
Project

Characterisation of functional diversity of the plant-specific SMH family of proteins (GP521/08/P452)

. Although each of them is ds-telomeric repeat binding, some of them are also G-rich the question whether the AtTRB proteins are telomere localized or whether they distinguishAtTRB proteins are members of ...

EB - Genetika a molekulární biologie

  • 2008 - 2010
    • •
  • 1 344 tis. Kč
    • •
  • 1 344 tis. Kč
    • •
  • GA ČR
Project

Dynamics of shelterin complex assembly (GAP205/12/0550)

quantitatively interactions within shelterin. Binding affinities of shelterin proteins involving nucleoprotein complexes at chromosome ends – telomeres. Telomeres shorten is a reverse transcriptase that extends

BO - Biofyzika

  • 2012 - 2015
    • •
  • 8 688 tis. Kč
    • •
  • 8 688 tis. Kč
    • •
  • GA ČR
Project

Molecular nature of evolutionary telomere transitions in Asparagales plants (GA17-09644S)

which largely depend on telomere-binding proteins (TBPs). RNA-Seq dataIn 2016, we identified unusual telomeres in Allium plants. Together with our earliear results, it is clear now that two telomere switc...

EB - Genetika a molekulární biologie

  • 2017 - 2019
    • •
  • 10 203 tis. Kč
    • •
  • 9 000 tis. Kč
    • •
  • GA ČR
Project

Molecular evolution and functional analysis of components of plant telomeres and telomerases (GA521/05/0055)

Telomeres are nucleoprotein structures protecting chromosome ends from degradation and fusions. Many organisms use telomerase, comprising telomere reverse with the evolution of novel types of telomeres. In addition to group...

EB - Genetika a molekulární biologie

  • 2005 - 2007
    • •
  • 3 792 tis. Kč
    • •
  • 3 792 tis. Kč
    • •
  • GA ČR
Project

Molecular analysis of the structure and function of typical and alternative telomeres in plants (GA204/02/0027)

" telomeres of [TTTAGGG]n sequence has been described and investigated. The aim of the proposed project is to increase a knowledge of structure of the "typical" telomeres, namely in the field of telomere-binding

EB - Genetika a molekulární biologie

  • 2002 - 2004
    • •
  • 4 982 tis. Kč
    • •
  • 2 843 tis. Kč
    • •
  • GA ČR
Project

Structural and functional components of plant telomeres (GA13-06943S)

) protein structure and interactions of plant telomeres; (ii) telomerase complex. Protein components involved in the formation of functional plant telomere complex telomere length, Nicotiana tabacum and Ar...

EB - Genetika a molekulární biologie

  • 2013 - 2017
    • •
  • 19 576 tis. Kč
    • •
  • 19 576 tis. Kč
    • •
  • GA ČR
Project

The dynamics of telomere-associated proteins and its relation to genome stability (LH13054)

of telomere-associated protein complexes in vitro and in vivo. The planned studies for the maintenance of genetic stability. The knowledge of telomeric protein dynamics will allow of telomere assembly whi...

EB - Genetika a molekulární biologie

  • 2013 - 2015
    • •
  • 1 849 tis. Kč
    • •
  • 1 849 tis. Kč
    • •
  • MŠMT
Project

Interaction partners of plant telomeres and telomerases (LH13052)

Telomeres are special structures at the chromosome ends maintained for fundamental understanding of telomere maintenace regulation and also of putative nontelomericfunctions of telomerase. Determination of interaction between te...

EB - Genetika a molekulární biologie

  • 2013 - 2015
    • •
  • 1 751 tis. Kč
    • •
  • 1 751 tis. Kč
    • •
  • MŠMT
Project

Understanding of HMGB1 protein involvement in maintaining genome stability (GA204/08/1530)

HMGB1 is a relatively abundant chromatin-associated protein and recent data of telomeres, the specific nucleoprotein structures forming chromosome ends and protecting telomere shortening or loss, and occasional telomere...

CE - Biochemie

  • 2008 - 2010
    • •
  • 4 887 tis. Kč
    • •
  • 4 887 tis. Kč
    • •
  • GA ČR
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