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Language reorganisation and naming deficit in temporal lobe epilepsy patients; assessment by functional magnetic resonance imaging and tractography (NT11536)
Temporal lobe resection is the most common type of epilepsy surgery. Modern decline, in particular naming abilities, following speech dominant temporal lobe seeded tractography in diagnostics of language function and organi...
FP - Ostatní lékařské obory
- 2010 - 2014 •
- 4 300 tis. Kč •
- 4 277 tis. Kč •
- MZ
Řešení projektu: 1. 9. 2010 - 31. 12. 2014
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Neuropathological analysis of human epileptic brain tissue correlation with proton magnetic resonance spectroscopy. (NF7411)
our understanding of ethiopathogenesis of mesial temporal lobe epilepsyBrain tissue from temporal lobectomies of refractory epileptic patients in both the archi- and neocortical temporal structures, area-specific ...
FH - Neurologie, neurochirurgie, neurovědy
- 2003 - 2005 •
- 4 304 tis. Kč •
- 3 970 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (92%)
Poskytovatel: Ministerstvo zdravotnictví
Impaired neurogenesis – a cause of psychiatric comorbidities in early onset temporal epilepsy? (LH15025)
-induced model of early onset temporal lobe epilepsy present project intends to find out possible biological links between epilepsy and behavioral deficits. WeChildhood–onset epilepsies are frequently associated wi...
FH - Neurologie, neurochirurgie, neurovědy
- 2015 - 2017 •
- 1 593 tis. Kč •
- 1 593 tis. Kč •
- MŠMT
Řešení projektu: 15. 10. 2015 - 31. 12. 2017
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Understanding of functional organization of temporal lobe epilepsy neuronal networks (NT14489)
Traditionally mesial temporal lobe epilepsy (TLE) is considered as a single disorder. Unsatisfactory results of its surgical treatment in ~30% of cases suggest that TLE involves group of closely related syndromes. One of the reasons...
FH - Neurologie, neurochirurgie, neurovědy
- 2013 - 2015 •
- 5 207 tis. Kč •
- 5 207 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2013 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
The role of neurodegeneration in pathogenesis, manifestations and prognosis of MTLE/HS - in vivo, ex vivo and in vitro perspective (NU22-04-00366)
Temporal lobe epilepsy as the most prevalent form of focal epilepsy poses of neurodegenerative pathways in epilepsy, mostly exploring neurodegeneration associated proteins isoforms and alpha-synuclein). Studies foc...
Neurosciences (including psychophysiology)
- 2022 - 2025 •
- 10 693 tis. Kč •
- 10 693 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2022 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Damage of interneurons within the hippocampus and dentate gyrus after status epilepticus in developing rats (GA304/04/0464)
Temporal lobe epilepsy represents majority of therapy-resistant epilepsies in patients. Many cases start during childhood. This epilepsy is characterized morphologically by hippocampanal sclerosis affecting mostly ...
EA - Morfologické obory a cytologie
- 2004 - 2006 •
- 2 715 tis. Kč •
- 2 715 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The mechanisms of respiratory and cardiac dysfunction responsible for the increased risk of sudden unexpected death in epilepsy. (NU21-04-00601)
Sudden unexpected death in epilepsy (SUDEP) is a major challenge in epilepsy research and practice. These deaths follow generalized tonic clonic seizures. They are caused by respiratory failure, preceded by transient cardiac and res...
Clinical neurology
- 2021 - 2024 •
- 10 656 tis. Kč •
- 10 656 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2021 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Proton Magnetic Resonance Spectroscopy Correlation with Neuropathological Findings in Patients with Mesial Temporal Lobe Epilepsy (GP309/02/D076)
Proton magnetic resonance spectroscopy (1H MRS) is a new diagnostic technique that permits in vivo determination of discrete biochemical changes within brain tissue. A major contribution of 1H MRS to evaluation of patients with mesial temporal
FH - Neurologie, neurochirurgie, neurovědy
- 2002 - 2005 •
- 846 tis. Kč •
- 846 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2002 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The role of high-frequency oscillations in the pathophysiology and presurgical diagnosis of drug-resistant neocortical epilepsy (NW24-08-00394)
of candidates for epilepsy surgery. Prospective studies and meta-analyses confirmed better of epileptogenicity. This discrepancy is more pronounced in neocortical epilepsy, where of HFOs in epilepsy surgery. Characterizing...
Neurosciences (including psychophysiology)
- 2024 - 2027 •
- 11 593 tis. Kč •
- 11 593 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2024 - 31. 12. 2027
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Therapeutic miRNA targeting in epilepsy Impact on excitability and beyond (GA23-05274S)
Temporal lobe epilepsy (TLE) is a neurological disorder characterized by recurrent seizures with severe impact on patients, their families and health systems. Despite the extensive research, the detailed pathophysiology of this dise...
Behavioral sciences biology
- 2023 - 2025 •
- 15 339 tis. Kč •
- 15 168 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2023 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Grantová agentura České republiky
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