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Project

The control of biocompatible thermosensitive polymer nanoparticles by low-molecular weight additives the study of underlying interactions (GAP205/11/1657)

The ability of the thermosensitive polymers to undergo huge but reversible of nanoparticles based on various thermosensitive homo- and co-polymers. Acrylamide- and ether-based polymers are chosen with diff...

CF - Fyzikální chemie a teoretická chemie

  • 2011 - 2013
  • 4 830 tis. Kč
  • 4 830 tis. Kč
  • GA ČR
Project

Thermoresponsive polymeric drug delivery systems for local radiotherapy (IAA400480616)

Thermoresponsive polymers are prospective systems for medical applications. One with a thermoresponsive polymer labelled with a suitable radionuclide. These polymers are namely well polymer is left at the place of ...

CD - Makromolekulární chemie

  • 2006 - 2008
  • 3 965 tis. Kč
  • 3 965 tis. Kč
  • AV ČR
Project

Double-step phase separation of temperature sensitive polymer systems influence of additives (GP203/07/P378)

"Smart" polymers are a class of materials that can expand or contract according to tiny changes in temperature, light, and a solvent or other external stimulus. The ability of the gels to undergo huge but reversible changes in volume allows ...

CF - Fyzikální chemie a teoretická chemie

  • 2007 - 2009
  • 920 tis. Kč
  • 920 tis. Kč
  • GA ČR
Project

Designing and characterization of novel thermosensitive polymer hydrogels (GA13-23392S)

Project is focused on the study of polymer hydrogels particularly acrylamide-based, which show the temperature induced phase transition (collapse). Variously modified polymer gels, e.g. two-component interpenetrating networks and na...

BM - Fyzika pevných látek a magnetismus

  • 2013 - 2016
  • 12 034 tis. Kč
  • 12 034 tis. Kč
  • GA ČR
Project

Self-organization of hydrophobic polymers with ionizable groups (IAA4050403)

The aim is synthesis of new types of hydrophobic polymers with ionizable groups content, and for polymers with photochromic groups (azobenzene), also by ultraviolet radiation (external parameters). The polymers will be rand...

CD - Makromolekulární chemie

  • 2004 - 2008
  • 5 627 tis. Kč
  • 5 627 tis. Kč
  • AV ČR
Project

Molecular Basis of Thermosensitive TRP Ion Channel Regulation in Nociceptive Neurons (GA19-03777S)

Thermosensitive Transient Receptor Potential (TRP) channels are excitatory ion channels that function as polymodal cellular sensors, detecting a wide range of proalgesic agents, endogenous products of inflammation and changes in temperature ...

Neurosciences (including psychophysiology)

  • 2019 - 2021
  • 6 364 tis. Kč
  • 6 046 tis. Kč
  • GA ČR
Project

Crosstalk between pH and temperature responsivity How it can be used for polymer nanoparticulate systems for biomedical applications? (LH14292)

of thermosensitive polymers have the extra advantage that they may exist as molecular solutionsPolymeric micelles recently attracted much attention in the development of drug delivery systems because of their nanometer-sca...

CC - Organická chemie

  • 2014 - 2016
  • 2 963 tis. Kč
  • 1 935 tis. Kč
  • MŠMT
Project

Composite nanoparticles with magnetically and light activated release of biologically active compounds (GA18-13323S)

The project is devoted to the synthesis of composite nanosystems whose magnetic cores based on ferrites will be coated by complex architectures with non-covalently attached biologically active compounds. The functional component of the shell will con...

Nano-materials (production and properties)

  • 2018 - 2022
  • 6 704 tis. Kč
  • 6 428 tis. Kč
  • GA ČR
Project

Smart pH- and temperaturesensitive hydrogels based on amphiphilic block copolymers with a gradient block (7AMB15FR039)

The project aims at synthesis of novel type of amphiphilic ionic di- and triblock-gradient copolymers and exploration of their ability to form smart, stimuli-responsive materials. The Nitroxide Mediated Polymerization will be exploited for t...

CD - Makromolekulární chemie

  • 2015 - 2016
  • 108 tis. Kč
  • 108 tis. Kč
  • MŠMT
Project

Preparation of multifunctional thermal responsive hydrogel for tumor-vascular normalization combined with radiation and immunotherapy (TF06000093)

The project is focused to preparation of immunoprotective nanopharmaceuticals suppressing the undesirable consequences of radio- and chemotherapy of tumors. The currently used chemical radioprotectant (Amifostin), which protects against genetic damag...

Organic chemistry

  • 2019 - 2021
  • 17 771 tis. Kč
  • 12 440 tis. Kč
  • TA ČR
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