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144 (0,151s)

Project

The role of Toll pathway in the regulation of tick immune response against tick-transmitted pathogens (GA20-05736S)

Tick Ixodes ricinus is a vector of Lyme disease and Tick-borne encephalitis in Europe and the Czech Republic. The tick immune system determines the tick vectorial a strategy for identification of novel tick

Immunology

  • 2020 - 2023
  • 8 524 tis. Kč
  • 8 524 tis. Kč
  • GA ČR
Project

Proteins of the tick iron metabolism pathway ? antigens for a new vaccine against ticks and tick-transmitted diseases (GP13-27630P)

Ticks are blood-feeding parasites and vectors of some of the most devastating is a common tick in the Czech Republic and Europe, transmitting tick-borne encephalitis of the hosts using recombinant tick proteins red...

ED - Fyziologie

  • 2013 - 2015
  • 3 220 tis. Kč
  • 3 220 tis. Kč
  • GA ČR
Project

IMMUNOMODULATORY EFFECTS OF TICK CYSTATINS (KJB500960702)

Tick saliva has been proven to facilitate transmission of important human the general effect of tick saliva on host immune mechanisms was characterised, little is known aboutimmunomodulatory functions of particular components in

EC - Imunologie

  • 2007 - 2009
  • 1 350 tis. Kč
  • 1 350 tis. Kč
  • AV ČR
Project

The effect of tick salivary molecules on replication of tick-borne encephalitis virus in innate immunity cells (GA14-25799S)

Tick-borne encephalitis virus (TBEV) is transmitted to humans by infected ticks and can cause severe encephalitis. Transmission of TBEV is facilitated by tick saliva is to understand how tick saliva and tick

EC - Imunologie

  • 2014 - 2016
  • 5 904 tis. Kč
  • 5 904 tis. Kč
  • GA ČR
Project

Prevention of Tick-borne Diseases Transmitted by Ticks of the Species IIxodes ricinus in the Czech Republic (NI5856)

The questionnaire investigating contacts with ticks, and awareness of ticks and tick-borne diseases in a representative sample of the youth population. Compilation of an information leaflet based upon the results of this qu...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2000 - 2001
  • 983 tis. Kč
  • 341 tis. Kč
  • MZ
Project

*Development of vaccine for protect transmission of ticks transmissed infections based on Ferritin-2 for veterinary and human use. (FR-TI3/156)

against ticks and pathogens transmitted by them (Borrelia, tick encephalitis etc.). By installing of the vaccine against ticks based on Ferritin-2, the Czech republic will become the first country on the world with this or...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2011 - 2014
  • 62 562 tis. Kč
  • 27 433 tis. Kč
  • MPO
Project

Comparative analysis of differential gene expression in Ixodes ricinus tick after infection with TBE virus and LB spirochetes (GA524/06/1479)

Ixodes ricinus tick is a principal vector of tick borne encephalitis virus diseases. Blood feeding is the subject of determinative importance in tick ontogenesis proteins. The array of up-regulated genes differs depending o...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2006 - 2008
  • 1 899 tis. Kč
  • 1 899 tis. Kč
  • GA ČR
Project

Effect of tick saliva cystatins on Th9 cells and the development of experimental asthma (GCP302/11/J029)

Host immunity against feeding ticks comprises immediate type of hypersensitivity with histamine directly affecting the tick. Ticks developed countermeasures facilitating both blood feeding and tick-borne pathogen t...

EC - Imunologie

  • 2011 - 2015
  • 4 824 tis. Kč
  • 4 824 tis. Kč
  • GA ČR
Project

Ticks and tick-borne pathogens new risks in the context of ongoing environmental changes (LUC23151)

Areas and local abundance of numerous species of ticks are currently increasing of developing tick-borne diseases are increasing dramatically, even in areas that have and complement each other. These are the following areas: I. The...

Microbiology

  • 2023 - 2026
  • 11 350 tis. Kč
  • 11 350 tis. Kč
  • MŠMT
Project

Functional characterization of cytokine binding molecules from tick saliva (GN23-07242I)

Ixodes ricinus ticks are among the most important disease vectors in Europe. Ticks secrete saliva containing hundreds of proteins that interfere with all types of host defense mechanisms. Our hypothesis based on data from other ...

Biochemistry and molecular biology

  • 2023 - 2026
  • 5 916 tis. Kč
  • 5 916 tis. Kč
  • GA ČR
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