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3 003 (0,09s)

Project

The role of proteins from Bir/Survivin family of genes in regulation of transcription by RNA polymerase II. (GA301/03/0333)

Regulation of transcription is based on interaction of RNA polymerase II homologue ofhuman Survivin is participating on transcription regulation disassembly during transcription regulation. Surviv...

EA - Morfologické obory a cytologie

  • 2003 - 2005
  • 4 776 tis. Kč
  • 4 776 tis. Kč
  • GA ČR
Project

The novel isoform of cyclin K is a partner of cdk12 kinase regulating eukaryotic transcription and alternative splicing (GAP305/11/1564)

of RNAP II is crucial for the regulation of transcription and co-transcriptional pre kinases (cdk). Cdk9 is one of these kinases; it regulates transcriptional elongation kinase activity and plays an impor...

EB - Genetika a molekulární biologie

  • 2011 - 2013
  • 5 282 tis. Kč
  • 5 089 tis. Kč
  • GA ČR
Project

Transcriptional regulation of Epstein–Barr oncovirus – biophysical implications for Rta-targeted therapy (GA23-05241S)

transcription regulator - Rta (Replication and transcription activator) as an innovative of Rta and another transcriptional regulator - Zta during EBV lytic transition and multiple sclerosis. As DNA t...

Biophysics

  • 2023 - 2025
  • 12 612 tis. Kč
  • 12 612 tis. Kč
  • GA ČR
Project

Study on tissue-specific aspects of transcriptional regulation of selected P-450 enzymes and drug transporters. (GA303/07/0128)

in gene expression.  The aim of the project is to study  transcriptional regulation some general aspects of the transcriptional regulation that have not been fully mechanisms of extrahepatal transcriptional

CE - Biochemie

  • 2007 - 2011
  • 5 045 tis. Kč
  • 5 045 tis. Kč
  • GA ČR
Project

Integrative analysis of the role of bZIP transcription factors in pollen maturation (GA522/09/0858)

genes and biological pathway(s) regulated by bZIP transcription factor complexes.. Different expression profiles of genes encoding male gametophytic transcription factors suggest the existence of specific mechanisms of

EF - Botanika

  • 2009 - 2012
  • 5 057 tis. Kč
  • 5 057 tis. Kč
  • GA ČR
Project

Regulation of transcription in eukaryotes (IAA552410)

CE - Biochemie

  • 1994 - 1996
  • 277 tis. Kč
  • 425 tis. Kč
  • AV ČR
Project

Artificial epigenetics Development of a eukaryotic bioorthogonal transcription system for gene expression manipulation in the cell. (GA17-03419S)

Natural DNA modifications are epigenetic signals that are vital for regulation of gene expression. Artificial DNA modifications possess immense potential with respect to modulate the way how RNA polymerase (the key enzyme of transcriptio...

EB - Genetika a molekulární biologie

  • 2017 - 2019
  • 9 537 tis. Kč
  • 9 072 tis. Kč
  • GA ČR
Project

Modifications and bioorthogonal reactions in the major groove of DNA for regulation of protein binding and gene expression (GA14-04289S)

groups for regulation (switching) of binding of proteins to DNA. The influence, methyltransferases, transcription factors etc.) and on in vitro transcription will be used to regulate and switch these interactions ...

CE - Biochemie

  • 2014 - 2016
  • 9 994 tis. Kč
  • 9 994 tis. Kč
  • GA ČR
Project

Structural studies of transcriptional regulators of the DeoR and GntR families involved in catabolic repression in Bacillus subtilis. (ME08016)

specific repressors and activators controlling the level of transcription of catabolic genes. Transcriptional repressors involved in catabolic repression mainly belong to one of thetwo large families of prokaryotic transcriptio...

CE - Biochemie

  • 2008 - 2012
  • 1 240 tis. Kč
  • 1 240 tis. Kč
  • MŠMT
Project

Expression of lincomycin biosynthetic gene cluster and its regulation (GA204/05/0616)

-specific regulators and organization of transcription units is indispensable forThe project aims in finding the organization of transcriptional units within the lincomycin biosynthetic cluster and identifying transcrip...

EB - Genetika a molekulární biologie

  • 2005 - 2007
  • 2 466 tis. Kč
  • 2 466 tis. Kč
  • GA ČR
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