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2 832 (0,158s)

Project

Nutritional and hormonal regulation of synthesis and transport fatty acids in insulin resistance (NR7888)

of Cd36 fatty acid transporter and transgenic SHR rats with expression of Cd36 or aP2. The role fatty acid binding proteins, fatty acid transporters and LPL activity on transport and utilization of NEFA a...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2006
  • 5 556 tis. Kč
  • 5 049 tis. Kč
  • MZ
Project

Analysis of the effects of Cd36 (fat) transgene in spontaneously hypertensive rats on clustering of cardiovascular risk factors (GA301/00/1636)

of CD36, a key protein of the cellular transport of fatty acids; 2)CD36 is located ontoSHR background restores normal expression of CD36 and improves cellular defects provided a strong evidence for the involvement...

EB - Genetika a molekulární biologie

  • 2000 - 2002
  • 2 780 tis. Kč
  • 1 919 tis. Kč
  • GA ČR
Project

Molecular mapping and positional cloning of genes that are responsible for clustering of cardiovascular risk factors (GA305/00/1646)

in the Cd26 gene that encodes a fatty acid transporter has been found to be responsible. However, the role of Cd36 in the pathogenesis of hypertension is unknown and at least oxide synthase (Nos3) and leptin gene (Lep), are linked ...

EB - Genetika a molekulární biologie

  • 2000 - 2002
  • 2 919 tis. Kč
  • 2 505 tis. Kč
  • GA ČR
Project

New metabolic pathways of lipid trafficking (LUAUS24040)

quantitative analysis of intra- and inter-cellular transport of lipids, specifically fatty acids and FAHFA lipokines. 1. Transcytosis in lipid transport 1.1 To trace the fate of fatty acids during transcytosis in relation to the pr...

Biochemistry and molecular biology

  • 2024 - 2027
  • 10 122 tis. Kč
  • 10 122 tis. Kč
  • MŠMT
Project

Modulation of Fatty Acid Reesterification in Adipose Tissue by Lipid Mediators (LH14040)

portion of fatty acids is reesterified, how are fatty acid transporters (e.g. CD36 and adipose tissue with respect to fatty acid transporter CD36 and composition of dietary specialized methods of mass spectrometry...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2014 - 2016
  • 1 910 tis. Kč
  • 1 910 tis. Kč
  • MŠMT
Project

The role of CD36 gene in pathogenesis of Alzheimer´s disease (NV18-04-00455)

The project is focused on the role of CD36 gene in the pathogenesis between CD36 gene and Alzheimer’s disease (AD). CD36 is involved in the removal. CD36 gene will be analyzed for all polymorphisms/mutations by the...

Clinical neurology

  • 2018 - 2021
  • 11 992 tis. Kč
  • 11 992 tis. Kč
  • MZ
Project

Metabolic flux analysis of carbohydrates and lipids in adipose tissue (LTAUSA17173)

. Multifunctional protein CD36 is also involved in fatty acid utilization via the interaction...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2017 - 2019
  • 2 284 tis. Kč
  • 2 284 tis. Kč
  • MŠMT
Project

Mixed myelodysplastic and myeloproliferative syndromes (MDS-MPS) (IZ4119)

The project propsal has 4 targets:1.to extend the number up to now examined MDS-MPS patients and to divide them in homogenous groups.2.to elaborate the dif.dg criteria.3.to find optimal therapy. 4.to study the CD36 decreased expression,apopt...

FD - Onkologie a hematologie

  • 1997 - 1999
  • 1 709 tis. Kč
  • 1 429 tis. Kč
  • MZ
Project

Using 13C and proton MR spectroscopy to study the role of fatty acid transport and accumulation in tissues in the pathogenesis of insulin resistance (GAP301/11/2418)

transport, their accumulation in tissues, the influence of glucose utilization...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2011 - 2014
  • 5 272 tis. Kč
  • 5 272 tis. Kč
  • GA ČR
Project

Changes of lipid metabolism and composition during colorectal carcinogenesis - the effects of butyrate and polyunsaturated fatty acids (GAP301/11/1730)

of cellular lipid structure and composition and investigate changes of lipid transporter proteins (FAT/CD36, caveolin-1), accumulation of cytoplasmic lipid droplets......

EB - Genetika a molekulární biologie

  • 2011 - 2013
  • 6 874 tis. Kč
  • 6 874 tis. Kč
  • GA ČR
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