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24 (0,067s) •

Project

Screening for defects in tryptophan metabolism. (IZ4097)

We intend to introduce simple and reliable methods,applicable to routine use for the detection of tryptophan metabolism abnormalities and make them a part of the routine programme for screening and diagnostics of the metabolic diseases.......

FG - Pediatrie

  • 1997 - 1999
    • •
  • 1 387 tis. Kč
    • •
  • 1 332 tis. Kč
    • •
  • MZ
Project

The deficit of cognitive function in scizophrenia and central serotonergic activity (NF6033)

The relationship betwen serotonin, neurocognitive deficit and regional brain activity will be elucidated by the use of tryptophan depletion, functional magnetic resonance and neurocognitive testing. We will compare the group of healthy volun...

FH - Neurologie, neurochirurgie, neurovědy

  • 2000 - 2002
    • •
  • 3 082 tis. Kč
    • •
  • 3 082 tis. Kč
    • •
  • MZ
Project

Placental tryptophan metabolism linking maternal inflammation and foetal neurodevelopmental disorders (NU20-01-00264)

in placental tryptophan metabolism and hence production of neuroactive molecules (e.g, placental tryptophan metabolism and infant neurodevelopment, thereby identifying......

Endocrinology and metabolism (including diabetes, hormones)

  • 2020 - 2023
    • •
  • 9 740 tis. Kč
    • •
  • 9 665 tis. Kč
    • •
  • MZ
Project

Driving Charge Transport in Chromophore-Protein Complexes through Tryptophan Pathways (GA21-05180S)

Sequential photoinduced charge transport along tryptophan-based "hopping" pathways will be investigated in protein (azurin) constructs containing a covalently attached organometallic photosensitizer, as well as in molecular donor-acceptor, a...

Biophysics

  • 2021 - 2024
    • •
  • 11 856 tis. Kč
    • •
  • 11 769 tis. Kč
    • •
  • GA ČR
Project

Polymer ligands as energy donors for lanthanides (GA203/04/1372)

, carbazole, tryptophane, carbostyril 124 etc. In non-polar solvents the core of micelles, the binding properties of tryptophan carboxy group and energy transfer from indol-methacryloyl-L-tryptophan-block-methyl methacrylat...

CD - Makromolekulární chemie

  • 2004 - 2006
    • •
  • 2 640 tis. Kč
    • •
  • 2 640 tis. Kč
    • •
  • GA ČR
Project

Picosecond Tryptophan Fluorescence Molecular Mechanistic Investigations Related to Blood Coagulation (IAA4040905)

. This project is limited to the latter one: picosecond tryptophan fluorescence of a factor...

BO - Biofyzika

  • 1999 - 2001
    • •
  • 1 403 tis. Kč
    • •
  • 434 tis. Kč
    • •
  • AV ČR
Project

Circadian regulation of kynurenine pathway enzymes in rat brain and peripheral organs (GA23-07184S)

Tryptophan catabolism leads to the production of kynurenines, which are required for energy metabolism. Their synthesis is regulated by several enzymes that respond to the increased energy demand, especially under pathological conditions of ...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2023 - 2025
    • •
  • 7 392 tis. Kč
    • •
  • 7 392 tis. Kč
    • •
  • GA ČR
Project

Microbial catabolites of tryptophan as modulators of intestinal health via aryl hydrocarbon receptor (GA20-00449S)

Microbial catabolites of tryptophan (MCT), were reported as ligands of aryl hydrocarbon receptor (AhR), having significant roles in intestinal physiology and pathophysiology. However, what is not being explored is a systems approach for all ...

Pharmacology and pharmacy

  • 2020 - 2022
    • •
  • 7 968 tis. Kč
    • •
  • 7 968 tis. Kč
    • •
  • GA ČR
Project

Cannabis use in pregnancy; effects on endocrine and immune functions of the placenta (GA23-07094S)

, the tryptophan and monoamine system, and the immune system....

Reproductive biology (medical aspects to be 3)

  • 2023 - 2025
    • •
  • 8 997 tis. Kč
    • •
  • 8 997 tis. Kč
    • •
  • GA ČR
Project

Electron Transfer in (Bio)Molecular Systems Time-Resolved Vibrational Spectroscopy and Theory (GA17-01137S)

tryptophan residues, characterization of Trp•+ intermediate in proteins, and electronic...

BO - Biofyzika

  • 2017 - 2019
    • •
  • 7 180 tis. Kč
    • •
  • 6 267 tis. Kč
    • •
  • GA ČR
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