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2 632 (0,197s) •

Project

Molecular mechanisms of proliferation during tumor progression and wound healing studied by profiling on single cell level (GA17-24441S)

behind two biological processes, wound healing and tumor progression. Sometimes, tumor growth is considered abnormal healing tissue. Unfortunately, complexBiological samples such as tissues, tumor biopsies and eve...

EB - Genetika a molekulární biologie

  • 2017 - 2020
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  • 7 236 tis. Kč
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  • 7 236 tis. Kč
    • •
  • GA ČR
Project

Study of expression and activation of apoptogenic caspases and of levels of their inhibitors in non-small cell lung carcinoma (NC6610)

Study of expression and activation of apoptogennic caspases and of levels of their inhibitors XIAP and survivin in human non-small cell lung carcinoma with the aim to evaluate their correlation with progression of this cancer disease.......

FD - Onkologie a hematologie

  • 2001 - 2003
    • •
  • 3 500 tis. Kč
    • •
  • 3 470 tis. Kč
    • •
  • MZ
Project

Elucidating the relationship between Trop2 expression and metastasis in cancer (GA24-11793S)

Trop2 is a transmembrane glycoprotein implicated in tumor progression, and its progression and dissemination, and Trop2 expression in non-tumor cell populations. We aim transition and plays a key role in tumor<...

Pathology

  • 2024 - 2026
    • •
  • 9 360 tis. Kč
    • •
  • 9 221 tis. Kč
    • •
  • GA ČR
Project

Altered function and composition of the chromatin-remodeling complex SWI/SNF in the progression of lung carcinoma and melanoma (NR9319)

The SWI/SNF chromatin-remodeling complex functions as a tumor suppressor and several of its subunits (Brm, Brg1 a INI1) were found to be mutated in human tumors the role of an abrogated function of SWI/SNF in the progression

FD - Onkologie a hematologie

  • 2007 - 2009
    • •
  • 7 871 tis. Kč
    • •
  • 7 860 tis. Kč
    • •
  • MZ
Project

Diagnosis and management of glioblastoma patients with rapid early progression before the initiation of adjuvant oncology treatment (NU20-03-00148)

localization of highly aggressive part of progressive tumor is needed alsoGlioblastoma is the most common and aggressive primary brain tumor. It is characterized by unfavorable prognosis with almost inevitable progress...

Oncology

  • 2020 - 2024
    • •
  • 9 842 tis. Kč
    • •
  • 9 806 tis. Kč
    • •
  • MZ
Project

Machine Learning-based Suite for Advanced Diffusion MRI Analysis of Brain Gliomas (NW25J-08-00023)

distinguish tumor progression from radiological alterations caused by treatment, affecting, and distinguish pseudoprogression from real tumor progression. The collected data will enhance the ability to separate ac...

Radiology, nuclear medicine and medical imaging

  • 2025 - 2028
    • •
  • 6 949 tis. Kč
    • •
  • 6 949 tis. Kč
    • •
  • MZ
Project

Discovery and development of novel tumor-suppressor-based reactivation cancer therapies (NW25-03-00073)

cancer growth and progression. An alternative “other side of the coin” approach silenced tumor suppressors instead of targeting the oncogenes. Tumor suppressors and their deactivation and downregulation is a crucial step i...

Oncology

  • 2025 - 2028
    • •
  • 19 501 tis. Kč
    • •
  • 18 255 tis. Kč
    • •
  • MZ
Project

Molecular characteristics of borderline ovarian tumors in relation to their biological behavior (NS10566)

characteristics of borderline ovarian tumors and comparing these characteristics to biological behavior of tumors. We will study frequency and modalities of inactivation of certain cellular pathways in tumor tissue. Analys...

FK - Gynekologie a porodnictví

  • 2009 - 2011
    • •
  • 4 935 tis. Kč
    • •
  • 4 815 tis. Kč
    • •
  • MZ
Project

Tetraspanins in Prostate Cancer Decoding Clinical Significance through Integration of Single Cell Analysis, Tumor Heterogeneity, and Tumor Microenvironment Interactions (NW24-03-00265)

, disease progression, and the tumor microenvironment. Through the utilization potential in regulating cancer progression. Therefore, the primary objective markers, and relevant clinicopathological parameters. By scrutinizi...

Oncology

  • 2024 - 2027
    • •
  • 12 633 tis. Kč
    • •
  • 12 633 tis. Kč
    • •
  • MZ
Project

Targeting genomic diversity in primary and recurrent gliomas for further understanding of brain tumor pathogenesis. (NU21-04-00100)

, progression and resistance to treatment. We assume that study addressing tumor evolution of clonal evolution, phylogenetics and progression of brain tumors. FurthermoreDiffuse gliomas are the most common primary ...

Oncology

  • 2021 - 2025
    • •
  • 13 243 tis. Kč
    • •
  • 13 193 tis. Kč
    • •
  • MZ
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