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3 432 (0,097s)

Project

Monoclonal antibodies for diagnosis of neuronal tumours and monitoring of neurodegenerative processes (IBS5052301)

Monoclonal antibodies against cytoskeletal proteins of neurons are used for identification of tumours or neuronal origin and represent usefull probes for monitoring with selected properties will be usefull for bett...

EA - Morfologické obory a cytologie

  • 2003 - 2005
  • 2 110 tis. Kč
  • 1 500 tis. Kč
  • AV ČR
Project

Tumours of human papillomavirus origin with different expression of MHC class I molecules theoretical principles of immunotherapy. (NR7807)

In this grant project it will be investigated whether there is a lack of immunological cross-reactivity between MHC class I positive and MHC class I negative tumours. It will be determined whether cytotoxic T lymphocytes recognise as targets...

FD - Onkologie a hematologie

  • 2004 - 2006
  • 4 218 tis. Kč
  • 2 404 tis. Kč
  • MZ
Project

New tumour diagnostic kits (OE10/2)

Finishing of characterization of antibodies against neurofilament triplet proteins. Reactivity of antibodies with phoshorylated epitopes will be tested, as well as reactivity of antibodies with material fixed under different conditions. Finishing of ...

FD - Onkologie a hematologie

  • 1996 - 1999
  • 7 345 tis. Kč
  • 6 325 tis. Kč
  • MŠMT
Project

Devitalization technique as a possible curative procedure in tumour therapy - preparation for clinical application (IBS5045113)

Our devitalization technique suggested for therapy of solid tumours is original surgical procedure that consists in tumour ischaemization by sutures of arterial and venous vessels leaving the tumour in organism. Re...

FD - Onkologie a hematologie

  • 2001 - 2004
  • 5 345 tis. Kč
  • 3 588 tis. Kč
  • AV ČR
Project

Acquisition of the mitochondrial genome by cells with damaged mitochondrial DNA restores the mitochondrial function and tumorigenic capacity (GA15-02203S)

syngeneic tumours with a long delay, resulting in metastases. These tumour cells were found to acquire mtDNA of the host origin, indicating intercellular transfer in a step-wise manner, from primary tumour via cir...

EB - Genetika a molekulární biologie

  • 2015 - 2017
  • 6 897 tis. Kč
  • 6 897 tis. Kč
  • GA ČR
Project

Cultivation of normal and tumour mammary epithelial cells with a 3T3 feeder layer. Utilization for the malignancy analysis of mammary carcinomas (GA312/97/1222)

of human normal and tumour mammary epithelial cells on a feeder layer of lethally, representing the majority of cell types that are present in the sample of the original , the comparison of the phenotypical characteristics of norma...

FD - Onkologie a hematologie

  • 1997 - 1999
  • 3 836 tis. Kč
  • 2 107 tis. Kč
  • GA ČR
Project

Antitumor DNA Vaccines. (IZ4069)

Induction of immunity to tumours of viral origin through inoculation with virus DNAs and coding for cytokines.Modification of virus oncoprotein genes to maintain their immunogenicity but remove their capacity to transform cells.......

FD - Onkologie a hematologie

  • 1997 - 1999
  • 9 112 tis. Kč
  • 6 573 tis. Kč
  • MZ
Project

Hereditary skin malignant melanoma in miniature pigs-characterization and experimental therapy (GA523/98/0229)

-glutamyltranspeptidase, alpha-mannosidase, tyrosinase, neuron-specific enolase), immunological matrix andmembrane proteins). Animals with tubero-modular form of tumour preliminary experiments, results in total regression of the pri...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1998 - 2000
  • 4 323 tis. Kč
  • 3 912 tis. Kč
  • GA ČR
Project

Papillae - tumours of microbial colonies (GA204/96/0251)

Growth of papillae, tumours on the surface or at the edge of the yeast colonies have not been so far systematically studied (with exception of their relation to the directed mutagenesis). Our aim is a) to classify the papillae from the point...

EA - Morfologické obory a cytologie

  • 1996 - 1998
  • 1 002 tis. Kč
  • 697 tis. Kč
  • GA ČR
Project

Regeneration of liver parenchyma of the patients suffering from metastasizing colorectal carcinoma stimulated by embolization of a portal vein branch and autologous haemopoietic progenitor cells. (NS10240)

is by a half of original time after PVE) the chance of further progression of a tumour in liver will be reduced and in the same time resecability of originally an inoperable liver tumour will increase.......

FJ - Chirurgie včetně transplantologie

  • 2009 - 2011
  • 5 516 tis. Kč
  • 5 516 tis. Kč
  • MZ
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