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1 680 (0,124s)

Project

The analysis of molecular organization of the retrovirus particle and interactions leading to its assembly (ME 904)

in the collaboratinglaboratories. The in vitro assembly method of virus like particles and study of formation of retroviral particles. This will be made possible by the employment formation, the laboratory of prof. McPhers...

EE - Mikrobiologie, virologie

  • 2007 - 2011
  • 2 391 tis. Kč
  • 2 391 tis. Kč
  • MŠMT
Project

Identification of potato mop-top virus (PMTV) based on the detection of virus proteins (GA522/01/1121)

The aim of this project is the study of physico-chemical properties of potato mop-top virus (PMTV) particles by the methods of molecular biology and by the immunochemical analysis based on the reactivity of antibodies prepared again...

EE - Mikrobiologie, virologie

  • 2001 - 2003
  • 5 689 tis. Kč
  • 3 092 tis. Kč
  • GA ČR
Project

Study of protein interaction involved in retrovirus particle assembly using two-hybrid systems (GP203/02/P020)

form immature virus particles that are then released from the plasma membrane,which is sufficient for forming virus-like particles. The Gag polyprotein pathway (M-PMV), Gag proteins first form intracytoplasmic

CE - Biochemie

  • 2002 - 2004
  • 835 tis. Kč
  • 698 tis. Kč
  • GA ČR
Project

The role of the ubiquitin and ubiquitin-like proteins in life cycle of the Mason-Pfizer monkey virus (GP301/06/P278)

of retroviral particle of Mason-Pfizer Monkey Virus (M-PMV). The goal is to find for the forming of infective retroviral particles have been proved. Tha major aim and transport of retroviral RNA, course of assembly and inf...

EE - Mikrobiologie, virologie

  • 2006 - 2008
  • 1 167 tis. Kč
  • 1 167 tis. Kč
  • GA ČR
Project

Role of retroviral matrix protein in virus particle targeting and interaction with plasma membrane. (GAP302/12/1895)

virus-like particles. We will also study interactions of MA with cellular factors biology. In this project, we will focus on late stage of the virus life cycle by studying the interactions of retroviral structural proteins...

EE - Mikrobiologie, virologie

  • 2012 - 2016
  • 8 835 tis. Kč
  • 8 835 tis. Kč
  • GA ČR
Project

Design, characterization and mechanism of action of novel inhibitors of HIV assembly (GA13-19561S)

, except for particle assembly and budding. Such compounds might complement current antiretroviral strategies and block the replication of resistant virus strains. Based on our of HIV capsid protein, thereby preventing virus

EB - Genetika a molekulární biologie

  • 2013 - 2016
  • 11 267 tis. Kč
  • 11 267 tis. Kč
  • GA ČR
Project

Analysis of immunochemical and biochemical properties of various isolates of potato virus a (PVA) (GA522/96/0398)

Potato virus A (PVA) is one of the earliest potyvirus to be described but is not yet sufficiently well studied. Athough we produced monoclonal antibodies to PVA several years ago, the antigenic properties of the virus and its isolat...

GE - Šlechtění rostlin

  • 1996 - 1998
  • 4 241 tis. Kč
  • 2 556 tis. Kč
  • GA ČR
Project

New materials and technologies for diagnostics od polyomaviruses in immunodeficient patients. (TH01010548)

To prepare type-specific recombinant antigens of polyomavirus BK (BKV) and Merkel cell polyomavirus (MCV) in a form of virus ? like particles (VLP) and to elaborate technologies for their binding to solid surfaces. To use these tool...

EE - Mikrobiologie, virologie

  • 2015 - 2017
  • 9 951 tis. Kč
  • 5 970 tis. Kč
  • TA ČR
Project

Structure of retroviral particle and intracellular transport of its components. (LH12011)

structural proteins. Particles of three retroviruses will be assembled in vitro. These 3 viruses are characteristic representatives of groups with various arrangements......

EE - Mikrobiologie, virologie

  • 2012 - 2015
  • 1 990 tis. Kč
  • 1 990 tis. Kč
  • MŠMT
Project

Assembly and budding of mouse mammary tumor virus (KJB400550517)

The goal of this project is the elucidation of the processes of assembly and budding of mouse mammary tumor virus (MMTV), the prototypical representative of the betaretrovirus genus. The study of virion formation will involve the development...

CE - Biochemie

  • 2005 - 2007
  • 894 tis. Kč
  • 894 tis. Kč
  • AV ČR
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