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Quantitative Analysis of Chemical Warfare Agents by GC/MS Method

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00007064%3AK13__%2F22%3AN0000033" target="_blank" >RIV/00007064:K13__/22:N0000033 - isvavai.cz</a>

  • Result on the web

    <a href="https://stm.bookpi.org/CTCB-V2/article/view/7121" target="_blank" >https://stm.bookpi.org/CTCB-V2/article/view/7121</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.9734/bpi/ctcb/v2/2282B" target="_blank" >10.9734/bpi/ctcb/v2/2282B</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Quantitative Analysis of Chemical Warfare Agents by GC/MS Method

  • Original language description

    Analysis of hazardous chemical substances in the Czech Republic is the main task of special chemical laboratories of the Fire and Rescue Service (FRS). The general criteria and requirements for an internal standard that may be used to determine chemical warfare agents (CWAs) using the gas chromatography coupled with mass detection (GC/MS) method were established. The aim of the work was the determination CWAs on all GC/MS systems of FRS, where no CWA standards are available. The determination is based on a GC/MS analysis of a mixture of a CWA with an internal standard, conversion of the total ion current (TIC) chromatogram to extracted-ion chromatogram at a particular m/z ratio, and calculation of the CWA concentration from the internal standard concentration, response factor and chromatographic peak areas. Internal standards for seven organophosphorus nerve-paralyzing agents and four blister agents were identified, and they were verified. The gradients of the linear functions of peak area and compound concentration were used to calculate the corresponding response factors. The measurements' linearity, repeatability, and accuracy were assessed.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    10400 - Chemical sciences

Result continuities

  • Project

    <a href="/en/project/VI20192022114" target="_blank" >VI20192022114: Research in Chemical Properties and Methods of Individual Protection against the Last Generation of Nerve Agents</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Current Topics on Chemistry and Biochemistry

  • ISBN

    978-93-5547-622-7

  • Number of pages of the result

    20

  • Pages from-to

    1-19

  • Number of pages of the book

    20

  • Publisher name

  • Place of publication

  • UT code for WoS chapter