Antibody Responses in Immunosuppressed Organ Allograft Recipients - Brief Review of the Current Literature

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F09%3A00002169" target="_blank" >RIV/00023001:_____/09:00002169 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Antibody Responses in Immunosuppressed Organ Allograft Recipients - Brief Review of the Current Literature

Original language description

With the rapidly growing application of new highly sensitive techniques for detection and definition of antibodies specific to HLA and non?HLA antigens, a significant number of studies have reported that de novo generation of antibodies after organ transplantation is associated with severe immunological complications and graft loss. The presence of donor specific complement?binding antibodies is confirmed by the finding of C4d deposits in the peritubular capillaries of the kidney graft ? a method now regularly used as a marker of antibody-mediated rejection. The clinical significance of various techniques for antibody identification with respect to the incidence of organ transplant rejection is however still a matter of discussion. The discrepancies inthe literature are most likely caused by variations in the approaches for antibody characterization and differences in patient cohorts and immunosuppressive protocols. In this concise review, we will discuss some recent developments in t

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

<a href="/en/project/NR9403" target="_blank" >NR9403: DIAGNOSTICS OF HUMORAL REJECTION FOR ORGAN TRANSPLANTATION</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Current Immunology Reviews

ISSN

1573-3955

e-ISSN

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Volume of the periodical

5

Issue of the periodical within the volume

2

Country of publishing house

AE - UNITED ARAB EMIRATES

Number of pages

6

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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