Both sublingual and supralingual routes of administration are effective in long-term allergen-specific immunotherapy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F11%3A00002450" target="_blank" >RIV/00023001:_____/11:00002450 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/11:10104202
Result on the web
<a href="http://dx.doi.org/10.2500/aap.2011.32.3423" target="_blank" >http://dx.doi.org/10.2500/aap.2011.32.3423</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2500/aap.2011.32.3423" target="_blank" >10.2500/aap.2011.32.3423</a>
Alternative languages
Result language
angličtina
Original language name
Both sublingual and supralingual routes of administration are effective in long-term allergen-specific immunotherapy
Original language description
The aim of this study was to confirm or refute the difference between efficacy of long-term specific immunotherapy (SIT) with standardized allergen vaccine consisting of six grass pollens (oat grass, orchard grass, fescue, rye grass, timothy grass, and rye) administered either by sublingual or by supralingual route. To investigate clinical and immunologic changes, 51 patients of a previous 1-year double-blind, placebo-controlled, randomized study were enrolled in an open randomized study that continuedover the next 3 years. Sublingual or supralingual immunotherapy (SLIT) was performed in the same way, keeping the drops under or on the tongue, respectively, for 1-2 minutes before swallowing them. Data about symptoms scores and rescue medication intakeduring grass pollen seasons, as well as skin-prick test results, levels of specific IgG, and IgE antibodies were collected after each pollen season. It was clearly shown that both routes of administration were effective, leading to a sign
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Allergy and asthma proceedings
ISSN
1088-5412
e-ISSN
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Volume of the periodical
32
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
142-150
UT code for WoS article
000289321100009
EID of the result in the Scopus database
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