MR spectroscopy as a tool for in vivo determination of steatosis in liver transplant recipients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F11%3A00002472" target="_blank" >RIV/00023001:_____/11:00002472 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s10334-011-0264-9" target="_blank" >http://dx.doi.org/10.1007/s10334-011-0264-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10334-011-0264-9" target="_blank" >10.1007/s10334-011-0264-9</a>

Result language

angličtina

Original language name

MR spectroscopy as a tool for in vivo determination of steatosis in liver transplant recipients

Original language description

Among several non-invasive methods of liver fat analysis, the most important role is played by MR imaging and spectroscopy (MRS). This study describes the 1H MRS at 3T measurement of liver fat volume fraction fat in a group of liver transplant patients,an at-risk group for the development of de novo steatosis. Linear and non-linear regression models were used to describe the relationship between fat and His. Strong correlation was found for both models with r =0.83-0.94 (p<0.001); a higher r was foundfor non-linear regression in all tested groups. Areas under receiver operation curves were calculated for cut points His >= 5% and >33% and were found in the range of 0.77-0.86. Fibrosis influences the calculation of fat and different slopes were obtained for fibrosis stage F0-F1 and F2-F3, respectively. Significant correlation was found between the results of histology and 1H MRS measurement of liver fat content. The method is suitable for non-invasive repetitive examination of liver fa

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Magnetic resonance materials in physics, biology and medicine

ISSN

0968-5243

e-ISSN

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Volume of the periodical

24

Issue of the periodical within the volume

5

Country of publishing house

DE - GERMANY

Number of pages

8

Pages from-to

297-304

UT code for WoS article

000295177400005

EID of the result in the Scopus database

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