Detection of Phl p 1, Phl p 5, Phl p 7 and Phl p 12 specific IgE antibodies in the sera of children and adult patients allergic to phleum pollen

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F12%3A00055967" target="_blank" >RIV/00023001:_____/12:00055967 - isvavai.cz</a>

Result on the web

<a href="http://ai.jsaweb.jp/pdf/061020339.pdf" target="_blank" >http://ai.jsaweb.jp/pdf/061020339.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2332/allergolint.11-OA-0372" target="_blank" >10.2332/allergolint.11-OA-0372</a>

Result language

angličtina

Original language name

Detection of Phl p 1, Phl p 5, Phl p 7 and Phl p 12 specific IgE antibodies in the sera of children and adult patients allergic to phleum pollen

Original language description

Background: Grasses belong to major sources of inhaled allergens. The knowledge of particular molecules responsible for hypersensitivity is of crucial importance for better understanding of individual differences among single allergic subjects and allergic populations living in various world-areas. Methods: Specific-IgE-antibodies against Phl p 1, Phl p 5, Phl p 7, Phl p 12 were detected in a group of 130 Phleum-allergic-subjects (82 children, 48 adults). Results: Phl p 1 antibodies were detected in most pediatric and adult patients, however, the children were associated with higher RAST classes more often. Anti-Phi p 5-antibodies were found more frequently in adults. An increase was observed in the number of pediatric patients reacting to Phi p 7 andPhl p 12. There were no differences in concentrations of specific-IgE against Phl p 5, Phl p 7 and Phl p 12 depending on age. Almost 10% of allergic children produced antibodies directed exclusively against minor allergens or did not prod

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Allergology international

ISSN

1323-8930

e-ISSN

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Volume of the periodical

61

Issue of the periodical within the volume

2

Country of publishing house

JP - JAPAN

Number of pages

8

Pages from-to

339-346

UT code for WoS article

000304891900018

EID of the result in the Scopus database

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