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Use of the Frank-Starling mechanism during exercise is linked to exercise-induced changes in arterial load

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F12%3A00056344" target="_blank" >RIV/00023001:_____/12:00056344 - isvavai.cz</a>

  • Result on the web

    <a href="http://ajpheart.physiology.org/content/302/1/H349.full.pdf+html" target="_blank" >http://ajpheart.physiology.org/content/302/1/H349.full.pdf+html</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1152/ajpheart.00147.2011" target="_blank" >10.1152/ajpheart.00147.2011</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Use of the Frank-Starling mechanism during exercise is linked to exercise-induced changes in arterial load

  • Original language description

    Effective arterial elastance(E(A)) is a measure of the net arterial load imposed on the heart that integrates the effects of heart rate(HR), peripheral vascular resistance( PVR), and total arterial compliance(TAC) and is a modulator of cardiac performance. To what extent the change in E(A) during exercise impacts on cardiac performance and aerobic capacity is unknown. We examined E(A) and its relationship with cardiovascular performance in 352 healthy subjects. Subjects underwent rest and exercise gatedscans to measure cardiac volumes and to derive E(A)[end-systolic pressure/stroke volume index(SV)], PVR[MAP/(SV*HR)], and TAC(SV/pulse pressure). E(A) varied with exercise intensity: the Delta E(A) between rest and peak exercise along with its determinants, differed among individuals and ranged from -44% to +149%, and was independent of age and sex. Individuals were separated into 3 groups based on their Delta E(A)I. Individuals with the largest increase in Delta E(A)(group 3;Delta E(A)

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NS10497" target="_blank" >NS10497: Metabolic factors involved in progression of chronic heart failure</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    American journal of physiology: Heart and circulatory physiology

  • ISSN

    0363-6135

  • e-ISSN

  • Volume of the periodical

    302

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    "H349"-"H358"

  • UT code for WoS article

    000298643800035

  • EID of the result in the Scopus database