HDL and Apolipoprotein A1 concentrations as markers of cholesterol efflux in middle-aged women: interaction with smoking

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F12%3A00057939" target="_blank" >RIV/00023001:_____/12:00057939 - isvavai.cz</a>

Result on the web

<a href="http://www.nel.edu/home.htm" target="_blank" >http://www.nel.edu/home.htm</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

HDL and Apolipoprotein A1 concentrations as markers of cholesterol efflux in middle-aged women: interaction with smoking

Original language description

OBJECTIVES: It has been demonstrated that the deleterious effect of smoking on the cardiovascular system is mediated through a decrease in protective HDL cholesterol. In addition, women are more sensitive to the negative effects of smoking, although theexact mechanism underlying this phenomenon is currently unknown. In this study, we evaluated whether smoking habits could modify the association of HDL cholesterol and apolipoprotein A1 (ApoA1) with reverse cholesterol transport (RCT), as measured by cholesterol efflux (CHE), in middle-aged women. DESIGN: The study group consisted of 39 healthy middle-aged women, 21 non-smokers (age 51.8 +/- 2.5 years, BMI 25.1 +/- 2.8 kg/m(2)) and 18 smokers (age 50.5 +/- 3.2 years, BMI 24.8 +/- 3.5 kg/m(2)). In addition to all traditional cardiovascular risk factors, CHE from macrophages, labelled during a 48-hour incubation in a medium containing [C-14] cholesterol, to plasma acceptors in study subjects was established as a marker of reverse choleste

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

<a href="/en/project/NT12170" target="_blank" >NT12170: Genetic determination of the nicotine dependence and the efficaccy of the nicotine dependence treatment</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology letters

ISSN

0172-780X

e-ISSN

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Volume of the periodical

33

Issue of the periodical within the volume

suppl. 2

Country of publishing house

SE - SWEDEN

Number of pages

5

Pages from-to

38-42

UT code for WoS article

000312175400008

EID of the result in the Scopus database

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