Natural postmenopause is associated with an increase in combined cardiovascular risk factors

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F12%3A00057943" target="_blank" >RIV/00023001:_____/12:00057943 - isvavai.cz</a>
Alternative codes found
RIV/67985807:_____/12:00383760
Result on the web
<a href="http://www.biomed.cas.cz/physiolres/pdf/61/61_587.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/61/61_587.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Natural postmenopause is associated with an increase in combined cardiovascular risk factors
Original language description
Cardiovascular disease, while rare in women of reproductive age, is the main cause of mortality in menopause. The purpose of our study was to determine the association of natural menopause with cardiovascular risk factors, including their clustering intometabolic syndrome (MS). A random 5 % representative population sample of women aged 45-54 years was examined. In 575 women, we were able to determine their natural reproductive aging status. Multiple regression analysis was used to calculate the association between age, menopausal status, and risk factors under study. After adjustment for age, there was an increase in the odds ratio of developing MS, as defined by NCEP (OR=2.0; 95 % CI [1.1; 3.7]), and an increase in plasma lipid ratios (total cholesterol/HDL-C, LDL-C/HDL-C, apolipoprotein-B/apolipoprotein-A1; p<0.05 for all) in postmenopausal women. Age, but not menopausal status, was associated with some single components of MS; only waist circumference significantly increased after
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Project
<a href="/en/project/NS10511" target="_blank" >NS10511: The effect of reproduction age on the sensitiveness of vascular wall to external, metabolic and genetic cardiovascular risk factors, longitudinal population study</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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