A novel biomarker-based approach for the detection of asymptomatic brain injury during catheter ablation of atrial fibrillation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00058895" target="_blank" >RIV/00023001:_____/14:00058895 - isvavai.cz</a>
Alternative codes found
RIV/00023884:_____/14:#0007185
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/jce.12325/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/jce.12325/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/jce.12325" target="_blank" >10.1111/jce.12325</a>
Alternative languages
Result language
angličtina
Original language name
A novel biomarker-based approach for the detection of asymptomatic brain injury during catheter ablation of atrial fibrillation
Original language description
BACKGROUND: Diffusion-weighted magnetic resonance imaging (DW-MRI) is a widely used method for studying of asymptomatic brain injury during catheter ablation of atrial fibrillation (AF). However, this technique lacks sensitivity for subtle or diffuse brain lesions. We investigated whether detection of the ablation-related brain injury can improve by assessment of a biomarker of brain damage-protein S100B. METHODS AND RESULTS: DW-MRI and assessment of S100B were performed in 58 patients undergoing radiofrequency catheter ablation of paroxysmal or persistent AF 1 day before and after the procedure. We observed no symptomatic neurological complications. S100B levels increased after ablation above the upper reference limit of 105 ng/L in 3 patients. One ofthem developed a new ischemic lesion on the DW-MRI. No acute lesions emerged on DW-MRI in the patients with normal postablation S100B levels. CONCLUSION: Serial assessment of serum protein S100B may improve detection of asymptomatic acut
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of cardiovascular electrophysiology
ISSN
1045-3873
e-ISSN
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Volume of the periodical
25
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
349-354
UT code for WoS article
000334165500003
EID of the result in the Scopus database
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