Survival with cardiac-resynchronization therapy in mild heart failure

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00059015" target="_blank" >RIV/00023001:_____/14:00059015 - isvavai.cz</a>
Result on the web
<a href="http://www.nejm.org/doi/pdf/10.1056/NEJMoa1401426" target="_blank" >http://www.nejm.org/doi/pdf/10.1056/NEJMoa1401426</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1056/NEJMoa1401426" target="_blank" >10.1056/NEJMoa1401426</a>

Result language
angličtina
Original language name
Survival with cardiac-resynchronization therapy in mild heart failure
Original language description
BackgroundThe Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy (MADIT-CRT) showed that early intervention with cardiac-resynchronization therapy with a defibrillator (CRT-D) in patients with an electrocardiographic pattern showing left bundle-branch block was associated with a significant reduction in heart-failure events over a median follow-up of 2.4 years, as compared with defibrillator therapy alone. MethodsWe evaluated the effect of CRT-D on long-term survival in the MADIT-CRT population. Post-trial follow-up over a median period of 5.6 years was assessed among all 1691 surviving patients (phase 1) and subsequently among 854 patients who were enrolled in post-trial registries (phase 2). All reported analyses were performed on an intention-to-treat basis. ResultsAt 7 years of follow-up after initial enrollment, the cumulative rate of death from any cause among patients with left bundle-branch block was 18% among patients randomly assigne
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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