Alcohol consumption and cognitive performance: a Mendelian randomization study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00059029" target="_blank" >RIV/00023001:_____/14:00059029 - isvavai.cz</a>
Alternative codes found
RIV/75010330:_____/14:00010707
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/add.12568/pdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/add.12568/pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/add.12568" target="_blank" >10.1111/add.12568</a>
Alternative languages
Result language
angličtina
Original language name
Alcohol consumption and cognitive performance: a Mendelian randomization study
Original language description
Aims To use Mendelian randomization to assess whether alcohol intake was causally associated with cognitive function. Design Mendelian randomization using a genetic variant related to alcohol intake (ADH1B rs1229984) was used to obtain unbiased estimatesof the association between alcohol intake and cognitive performance. Setting Europe. Participants More than 34 000 adults. Measurements Any versus no alcohol intake and units of intake in the previous week was measured by questionnaire. Cognitive function was assessed in terms of immediate and delayed word recall, verbal fluency and processing speed. Findings Having consumed any versus no alcohol was associated with higher scores by 0.17 standard deviations (SD) [95% confidence interval (CI) = 0.15, 0.20] for immediate recall, 0.17 SD (95% CI = 0.14, 0.19) for delayed recall, 0.17 SD (95% CI = 0.14, 0.19) for verbal fluency and 0.12 SD (95% CI = 0.09, 0.15) for processing speed. The minor allele of rs1229984 was associated with reduced
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Addiction
ISSN
0965-2140
e-ISSN
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Volume of the periodical
109
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
1462-1471
UT code for WoS article
000340566600014
EID of the result in the Scopus database
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