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Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised controlled trial

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00059031" target="_blank" >RIV/00023001:_____/14:00059031 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.sciencedirect.com/science/article/pii/S0140673614611764" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0140673614611764</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/S0140-6736(14)61176-4" target="_blank" >10.1016/S0140-6736(14)61176-4</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised controlled trial

  • Original language description

    Background An increasing number of patients with heart failure receive implantable cardioverter-defibrillators (ICDs) or cardiac resynchronisation defibrillators (CRT-Ds) with telemonitoring function. Early detection of worsening heart failure, or upstream factors predisposing to worsening heart failure, by implant-based telemonitoring might enable pre-emptive intervention and improve outcomes, but the evidence is weak. We investigated this possibility in IN-TIME, a clinical trial. Findings We enrolled716 patients, of whom 664 were randomly assigned (333 to telemonitoring, 331 to control). Mean age was 65.5 years and mean ejection fraction was 26%. 285 (43%) of patients had NYHA functional class II and 378 (57%) had NYHA class III. Most patients received CRT-Ds (390; 58.7%). At 1 year, 63 (18.9%) of 333 patients in the telemonitoring group versus 90 (27.2%) of 331 in the control group (p=0.013) had worsened composite score (odds ratio 0.63, 95% CI 0.43-0.90). Ten versus 27 patients di

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Lancet

  • ISSN

    0140-6736

  • e-ISSN

  • Volume of the periodical

    384

  • Issue of the periodical within the volume

    9943

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    583-590

  • UT code for WoS article

    000340573300030

  • EID of the result in the Scopus database