Bilateral oophorectomy may have an unfavorable effect on glucose metabolism compared with natural menopause

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00059069" target="_blank" >RIV/00023001:_____/14:00059069 - isvavai.cz</a>
Alternative codes found
RIV/00064190:_____/14:#0000823
Result on the web
<a href="http://www.biomed.cas.cz/physiolres/pdf/63%20Suppl%203/63_S395.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/63%20Suppl%203/63_S395.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Bilateral oophorectomy may have an unfavorable effect on glucose metabolism compared with natural menopause
Original language description
The incidence of diabetes mellitus is rising worldwide. The aim of this prospective epidemiological study was to compare the effects of natural and surgical menopause on parameters of glucose metabolism. In a group of 587 repeatedly examined women, witha baseline age of 45-55 years, the following subgroups of women were separated: those after bilateral oophorectomy (BO, n=37) and those in natural menopause (NAT, n=380) including women menopausal already at baseline (POST, n=89). The study parameters including glycemia, insulinemia, HOMA-IR and beta-cell function using HOMA-beta were determined at baseline and 6 years later. Over the study period, there was a marked rise in prediabetic and diabetic values of fasting glycemia; the percentage of women with diabetic values increased in the NAT (from 0.8 % to 3.9 %) and POST (from 2.2 % to 9.0 %) subgroups, with the highest prevalence in the BO subgroup (from 8.1 % to 10.8 %). While, among women with non-diabetic fasting glycemia, an incre
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Project
<a href="/en/project/NT14008" target="_blank" >NT14008: The influence of menopause on the development of cardiometabolic risk and signs of vascular damage - longitudinal study.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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