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The HLA-net GENE[RATE] pipeline for effective HLA data analysis and its application to 145 population samples from Europe and neighbouring areas

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00059159" target="_blank" >RIV/00023001:_____/14:00059159 - isvavai.cz</a>

  • Result on the web

    <a href="http://onlinelibrary.wiley.com/doi/10.1111/tan.12356/pdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/tan.12356/pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/tan.12356" target="_blank" >10.1111/tan.12356</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The HLA-net GENE[RATE] pipeline for effective HLA data analysis and its application to 145 population samples from Europe and neighbouring areas

  • Original language description

    In this review, we present for the first time an integrated version of the GENE[RATE] computer tools which have been developed during the last 5 years to analyse human leukocyte antigen (HLA) data in human populations, as well as the results of their application to a large dataset of 145 HLA-typed population samples from Europe and its two neighbouring areas, North Africa and West Asia, now forming part of the GENE[VA] database. All these computer tools and genetic data are, from now, publicly availablethrough a newly designed bioinformatics platform, HLA-net, here presented as a main achievement of the HLA-NET scientific programme. The GENE[RATE] pipeline offers user-friendly computer tools to estimate allele and haplotype frequencies, to test Hardy-Weinberg equilibrium (HWE), selective neutrality and linkage disequilibrium, to recode HLA data, to convert file formats, to display population frequencies of chosen alleles and haplotypes in selected geographic regions, and to perform ge

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EC - Immunology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Tissue Antigens

  • ISSN

    0001-2815

  • e-ISSN

  • Volume of the periodical

    83

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    17

  • Pages from-to

    307-323

  • UT code for WoS article

    000334356100001

  • EID of the result in the Scopus database