Magnetic La1-xSrxMnO3 nanoparticles as contrast agents for MRI: the parameters affecting H-1 transverse relaxation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F15%3A00059352" target="_blank" >RIV/00023001:_____/15:00059352 - isvavai.cz</a>

Result on the web

<a href="http://link.springer.com/article/10.1007%2Fs11051-014-2848-6" target="_blank" >http://link.springer.com/article/10.1007%2Fs11051-014-2848-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11051-014-2848-6" target="_blank" >10.1007/s11051-014-2848-6</a>

Result language

angličtina

Original language name

Magnetic La1-xSrxMnO3 nanoparticles as contrast agents for MRI: the parameters affecting H-1 transverse relaxation

Original language description

Magnetic nanoparticles of the La1-xSrxMnO3 perovskite phase (x = 0.20-0.45) were synthesized by a sol-gel method followed by thermal and mechanical treatments. The particles were coated with a uniform silica shell, and differential centrifugation yielded a product with high colloidal stability in water. X-ray powder diffraction (XRD) data showed that the mechanical processing did not affect the lattice parameters of the magnetic cores but only reduced their mean size d(XRD). The magnetic properties of the bare particles were mainly controlled by the chemical composition and were also affected by the size of the particles. Subsequent silica coating led to an effective decrease in magnetization. Relaxometry measurements were focused primarily on colloids using magnetic cores of the same size (d(XRD) approximate to 20 nm) and different compositions, and coated with a shell measuring approximately 20 nm in thickness. The exceedingly high transverse relaxivities [r(2-)(20 degrees C) = 290-430 s(-1) mmol(-1) L at B-0 = 0.5 T] of the samples exhibited pronounced temperature dependence and correlated very well with the magnetic data. Additional samples differing in the size of the cores and silica shell thickness were prepared as well to analyze the effect of the particles on H-1 transverse relaxation. The results suggest that the dominant regime of transverse relaxation is the static dephasing regime.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of nanoparticle research

ISSN

1388-0764

e-ISSN

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Volume of the periodical

17

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

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UT code for WoS article

000352165900001

EID of the result in the Scopus database

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