Sequential hybrid CryoMaze ablation versus surgical CryoMaze alone for the treatment of atrial fibrillation (SurHyb): study protocol for a randomized controlled trial

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F16%3A00060081" target="_blank" >RIV/00023001:_____/16:00060081 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12110/16:43891903 RIV/00216224:14110/16:00092164 RIV/00023884:_____/16:#0007153

Result on the web

<a href="http://trialsjournal.biomedcentral.com/articles/10.1186/s13063-016-1634-4" target="_blank" >http://trialsjournal.biomedcentral.com/articles/10.1186/s13063-016-1634-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13063-016-1634-4" target="_blank" >10.1186/s13063-016-1634-4</a>

Result language

angličtina

Original language name

Sequential hybrid CryoMaze ablation versus surgical CryoMaze alone for the treatment of atrial fibrillation (SurHyb): study protocol for a randomized controlled trial

Original language description

Background: Atrial fibrillation is common in patients with structural heart disease who are undergoing cardiac surgery. Surgical CryoMaze has been shown to be an effective treatment in several trials, but success rates have varied considerably, between 47-95 %. The sequential hybrid approach, combining surgical CryoMaze followed by radiofrequency catheter ablation, can achieve high freedom from atrial arrhythmias, even when rigorous methods to detect arrhythmias after the procedure are used. However, data from randomized trials comparing hybrid ablations to surgical ablations alone are lacking. Methods/Design: The SurHyb study is a prospective, multicenter, randomized study. Patients with persistent or long-standing persistent atrial fibrillation will be randomized to either surgical CryoMaze alone or surgical CryoMaze followed by catheter ablation 3 months post-surgery. The primary outcome measure is arrhythmia-free survival without class I or III antiarrhythmic drugs, which will be evaluated using 7-day ECG Holter monitoring at 24 months. A total of 260 patients will be investigated from three medical centers in the Czech Republic to obtain the relevant information. Discussion: This is the first randomized study that compares surgical CryoMaze alone with the staged hybrid surgical CryoMaze followed by catheter ablation in patients with persistent or long-standing persistent atrial fibrillation. These results will contribute to the optimization of the treatment for these patients.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Trials

ISSN

1745-6215

e-ISSN

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Volume of the periodical

17

Issue of the periodical within the volume

October 24

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

"art. no. 518"

UT code for WoS article

000386077600003

EID of the result in the Scopus database

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