Clinical predictors of complications in patients with left-sided infective endocarditis: A retrospective study of 206 episodes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F19%3A00078114" target="_blank" >RIV/00023001:_____/19:00078114 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/19:10395653 RIV/00216208:11150/19:10395653 RIV/00179906:_____/19:10395653
Result on the web
<a href="http://www.elis.sk/download_file.php?product_id=6240&session_id=gvgcob1dg3u7vuk2vnfp43j311" target="_blank" >http://www.elis.sk/download_file.php?product_id=6240&session_id=gvgcob1dg3u7vuk2vnfp43j311</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/BLL_2019_082" target="_blank" >10.4149/BLL_2019_082</a>
Alternative languages
Result language
angličtina
Original language name
Clinical predictors of complications in patients with left-sided infective endocarditis: A retrospective study of 206 episodes
Original language description
PURPOSE: Early identification of specific patient subgroups at high risk of developing life-threatening infective endocarditis (IE) complications is of paramount importance. Better stratification may allow more intensive treatment of these patients and positively influences clinical outcomes. METHODS: We carried out a retrospective survey of consecutive left-sided IE adult patients, admitted over a 15-year period to two main tertiary care centres in the Czech Republic. RESULTS: Among a group of 196 patients (155 males; median age 64 years), a total of 206 left-sided IE episodes were identified. Perivalvular extension of infection was most frequently seen in prosthetic aortic valve endocarditis (OR 6.706, p<0.0001). Valve prolapse/perforation during IE episodes was significantly associated with mitral valve IE (OR 2.136, p=0.026) and vegetation length (OR 1.055, p=0.009). Septic shock was significantly related to two main risk factors: S. aureus infection (OR 8.459, p=<0.0001) and smoking (OR 8.403, p=0.001). Mitral valve IE with a vegetation length >= 13 mm was the strongest risk factor for this complication (OR 3.24, p=0.001), followed by S. aureus infection (OR 3.59, p=0.002). Finally, septic shock (OR 6.000, p=0.001) represented the most important risk factor of in-hospital mortality. CONCLUSIONS: This study provides the most detailed profile of complication predictors related to left-sided IE in Central Europe. Early individual stratification of IE related occurrence of complications might help to decrease extremely high morbidity and mortality of this disease (Tab. 5, Ref. 37).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
—
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bratislavské lekárske listy
ISSN
0006-9248
e-ISSN
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Volume of the periodical
120
Issue of the periodical within the volume
7
Country of publishing house
SK - SLOVAKIA
Number of pages
6
Pages from-to
510-515
UT code for WoS article
000475423100005
EID of the result in the Scopus database
2-s2.0-85073114186