Serum albumin in patients undergoing transcatheter aortic valve replacement: A meta-analysis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F19%3A00078445" target="_blank" >RIV/00023001:_____/19:00078445 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/19:10399507 RIV/00064165:_____/19:10399507

Result on the web

<a href="https://rcm.imrpress.com/article/2019/2153-8174/2153-8174-20-3-161.shtml" target="_blank" >https://rcm.imrpress.com/article/2019/2153-8174/2153-8174-20-3-161.shtml</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.31083/j.rcm.2019.03.524" target="_blank" >10.31083/j.rcm.2019.03.524</a>

Result language

angličtina

Original language name

Serum albumin in patients undergoing transcatheter aortic valve replacement: A meta-analysis

Original language description

Transcatheter aortic valve replacement is becoming a more common therapeutic option for the treatment of aortic stenosis in patients at high risk for invasive surgery, but detecting which patients will benefit clinically can be challenging. Hypoalbuminemia is a useful prognostic marker for chronic inflammation in this population. We carried out a systematic review and meta-analysis of studies evaluating the prognostic value of serum albumin level in patients undergoing transcatheter aortic valve replacement. A literature search of PubMed, Embase, ScienceDirect, Web of Science, SciELO, BIOSIS, Wanfang, and CNKI databases was conducted. Articles published between January 2000 and December 2017 reporting on the prognostic value of low levels of serum albumin in patients undergoing transcatheter aortic valve replacement were analyzed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. 11 studies including 6456 patients met inclusion criteria for metaanalysis. A lower serum albumin level was associated with a lower survival rate at follow-up in patients who underwent transcatheter aortic valve replacement. A subgroup analysis of eight studies reporting adjusted hazard ratios indicated that low serum albumin was independently correlated with increased post-operative mortality. The hazard ratio of mortality risk associated with each 1 g/dL increment in serum albumin level was 0.46, suggesting a potential dose-response relationship between increased serum albumin level and increased survival rate in patients undergoing transcatheter aortic valve replacement. This meta-analysis provides strong evidence for the utility of serum albumin as a prognostic marker in aortic stenosis patients undergoing transcatheter aortic valve replacement, with low serum albumin levels (2.5-3.5 g/dL) suggesting poor prognosis.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Reviews in Cardiovascular Medicine

ISSN

1530-6550

e-ISSN

—

Volume of the periodical

20

Issue of the periodical within the volume

3

Country of publishing house

CN - CHINA

Number of pages

9

Pages from-to

161-169

UT code for WoS article

000488218700006

EID of the result in the Scopus database

2-s2.0-85073114817