A lattice-tip temperature-controlled radiofrequency ablation catheter for wide thermal lesions: first-in-human experience with atrial fibrillation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F20%3A00079673" target="_blank" >RIV/00023001:_____/20:00079673 - isvavai.cz</a>

Alternative codes found

RIV/00023884:_____/20:00008792

Result on the web

<a href="https://reader.elsevier.com/reader/sd/pii/S2405500X20300086?token=B1F690BE6CAE9AB7AFF86CC3A5E9FF2DBB91ED9607E2B9D761A8303AD478A57E9C15107C59B3C624C6DB3ED92F285685" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S2405500X20300086?token=B1F690BE6CAE9AB7AFF86CC3A5E9FF2DBB91ED9607E2B9D761A8303AD478A57E9C15107C59B3C624C6DB3ED92F285685</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jacep.2019.12.015" target="_blank" >10.1016/j.jacep.2019.12.015</a>

Result language

angličtina

Original language name

A lattice-tip temperature-controlled radiofrequency ablation catheter for wide thermal lesions: first-in-human experience with atrial fibrillation

Original language description

Objectives: This study sought to evaluate the safety and acute performance of the lattice tip for the treatment of atrial flutter and fibrillation (AF). Background: A novel catheter using an expandable lattice structure with a wide thermal footprint incorporating multiple surface thermocouples/mini-electrodes has been designed for high-resolution mapping and high-current, temperature-controlled radiofrequency ablation (RFA). Methods: Patients with typical right atrial flutter or AF were prospectively enrolled in a single-arm study at 3 centers. Patients with atrial flutter underwent cavotricuspid isthmus (CTI) ablation. Patients with paroxysmal AF underwent pulmonary vein isolation (PVI) and CTI if desired, and for patients with persistent AF, mitral isthmus and left atrial roof lines were also permitted. Mapping was performed with the lattice (Sphere-9) catheter and a novel compatible electroanatomic mapping system (Prism-1). RFA was performed in a point-by-point fashion (Tmax, 73°C to 80°C; range 2 to 7 s). Patients were followed for 3 months. Results: A total of 71 patients underwent ablation: 65 PVI (38% with persistent AF) and 22 mitral isthmus, 24 roof, and 48 CTI lines. PVI was achieved in 64 of 65 (98.5%) by using the lattice alone and required a mean of 2.7 ± 0.70 RFA min. Mitral block was achieved in 100% by using 11.5 ± 10.7 applications and 1.0 ± 0.92 RFA min; only 1 patient required adjunctive epicardial coronary sinus ablation. Roof line and CTI block were achieved in 95.8% and 100% of patients, using 4.9 ± 1.9 and 5.9 ± 3.1 applications for 0.4 ± 0.16 and 0.5 ± 0.24 RFA min, respectively. At 3 months, there were no deaths, strokes, tamponade, or atrioesophageal fistula. Conclusions: This first-in-human study demonstrated clinical feasibility and safety for rapid high-current, temperature-controlled point-by-point PVI and linear ablation. © 2020 The Authors

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

JACC Clinical Electrophysiology

ISSN

2405-500X

e-ISSN

—

Volume of the periodical

6

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

13

Pages from-to

507-519

UT code for WoS article

000602737800005

EID of the result in the Scopus database

2-s2.0-85084371935