Predictors of physical capacity 6 months after implantation of a full magnetically levitated left ventricular assist device: an analysis from the ELEVATE registry
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F20%3A00079916" target="_blank" >RIV/00023001:_____/20:00079916 - isvavai.cz</a>
Result on the web
<a href="https://reader.elsevier.com/reader/sd/pii/S1071916419306505?token=8E10DF735509623C0D48FE1F4F41F4E1C19BBB5FCCFF2E299B82D91D26FBD2F8423D8DB6BED6FC999FD71F92862CF3EE" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S1071916419306505?token=8E10DF735509623C0D48FE1F4F41F4E1C19BBB5FCCFF2E299B82D91D26FBD2F8423D8DB6BED6FC999FD71F92862CF3EE</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.cardfail.2020.04.004" target="_blank" >10.1016/j.cardfail.2020.04.004</a>
Alternative languages
Result language
angličtina
Original language name
Predictors of physical capacity 6 months after implantation of a full magnetically levitated left ventricular assist device: an analysis from the ELEVATE registry
Original language description
Background: In patients with a continuous-flow left ventricular assist device, preimplant predictors of poor physical performance are not well-described. We aimed to identify predictors of inability to walk more than 300 m on 6-minute walk test (6MWT) 6 months after HeartMate 3 implantation. Methods and Results: Using data from the European Registry of Patients Implanted With a Full Magnetically Levitated LVAD, patients with available 6MWT at 6 months after implantation were included (N = 194) and grouped according to 6MWT distance (6MWD) of >300 m (n = 150) or 6MWD of <300 m (n = 44). Patients walking <300 m were older (60 +/- 10 vs 52 +/- 12 years; P <.001), more often New York Heart Association functional class IV (63% vs 42%; P =.03), and more often had type 2 diabetes (43% vs 17%; P <.001) at implantation. Atrial fibrillation was seen in 57% in those with a 6MWT of <300 m vs 31% in those walking longer (P <.002). Further, hemoglobin and estimated glomerular filtration rate was lower in those walking < 300 m (both P <.01). In multivariable regression analysis, independent predictors of a 6MWD of <300 m were: atrial fibrillation (odds ratio [OR], 3.22; 95% confidence interval [CI], 1.12-8.67), older age (OR for 10-year increment, 2.81; 95% CI, 1.55-5.07), New York Heart Association functional class IV (OR, 3.37; 95% CI, 1.27-8.98), and Interagency Registry for Mechanically Assisted Circulatory Support profile 1 or 2 (OR, 6.53; 95% CI, 1.92-22.19). Conclusions: Six months after HeartMate 3 implantation, 77% of patients walked >300 meters in 6 minutes. Apart from age and measures of heart failure severity, atrial fibrillation at implantation is an independent predictor of low 6MWD at 6 months after implantation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of cardiac failure
ISSN
1071-9164
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
580-587
UT code for WoS article
000551280100009
EID of the result in the Scopus database
2-s2.0-85086370282