Critical analysis of non-thermal plasma-driven modulation of immune cells from clinical perspective

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F20%3A00080085" target="_blank" >RIV/00023001:_____/20:00080085 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/1422-0067/21/17/6226/htm" target="_blank" >https://www.mdpi.com/1422-0067/21/17/6226/htm</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ijms21176226" target="_blank" >10.3390/ijms21176226</a>

Result language

angličtina

Original language name

Critical analysis of non-thermal plasma-driven modulation of immune cells from clinical perspective

Original language description

The emerged field of non-thermal plasma (NTP) shows great potential in the alteration of cell redox status, which can be utilized as a promising therapeutic implication. In recent years, the NTP field considerably progresses in the modulation of immune cell function leading to promising in vivo results. In fact, understanding the underlying cellular mechanisms triggered by NTP remains incomplete. In order to boost the field closer to real-life clinical applications, there is a need for a critical overview of the current state-of-the-art. In this review, we conduct a critical analysis of the NTP-triggered modulation of immune cells. Importantly, we analyze pitfalls in the field and identify persisting challenges. We show that the identification of misconceptions opens a door to the development of a research strategy to overcome these limitations. Finally, we propose the idea that solving problems highlighted in this review will accelerate the clinical translation of NTP-based treatments.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10608 - Biochemistry and molecular biology

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International journal of molecular sciences

ISSN

1661-6596

e-ISSN

—

Volume of the periodical

21

Issue of the periodical within the volume

17

Country of publishing house

CH - SWITZERLAND

Number of pages

24

Pages from-to

"art. no. 6226"

UT code for WoS article

000569583400001

EID of the result in the Scopus database

2-s2.0-85090179717