Spectrum of postmortem autopsy findings in native and surgically corrected hearts with congenital malformations: a 10-year single-center experience
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F21%3A00080629" target="_blank" >RIV/00023001:_____/21:00080629 - isvavai.cz</a>
Alternative codes found
RIV/00064190:_____/21:N0000086 RIV/00216208:11120/21:43920773 RIV/00064203:_____/21:10417625 RIV/00216208:11130/21:10417625
Result on the web
<a href="https://reader.elsevier.com/reader/sd/pii/S1054880720301137?token=8EA0566BAE052422281BDA21B2AEB9EB4C5F26AB9AC65E6F9084D2FD483D608A1933FE210E54FFDB0549F8F606FCEECE" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S1054880720301137?token=8EA0566BAE052422281BDA21B2AEB9EB4C5F26AB9AC65E6F9084D2FD483D608A1933FE210E54FFDB0549F8F606FCEECE</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.carpath.2020.107309" target="_blank" >10.1016/j.carpath.2020.107309</a>
Alternative languages
Result language
angličtina
Original language name
Spectrum of postmortem autopsy findings in native and surgically corrected hearts with congenital malformations: a 10-year single-center experience
Original language description
Objectives: We reviewed a spectrum of congenital heart defects assessed in our center between 1/2010 and 4/2020, evaluated their gross anatomy, assessed the age distribution, evaluated performed surgical procedures, and correlated gross and ultrasound findings. Methods: All necroptic cases and explanted hearts that underwent specialized cardiac autopsy were included in this study. Autopsy findings including gross description of congenital heart defects together with echocardiographic findings were retrospectively assessed. In surgically corrected hearts, the operation records were included as well. All congenital heart defects and surgical procedures were subclassified into main and additional category. Results: The study included 92 necroptic cases of live-born children, 7 stillbirths, 2 cases of young adults, 50 induced abortions, and 5 explanted hearts, with median age 36 weeks. The most frequently encountered leading congenital heart defects were hypoplastic left heart syndrome, aortic stenosis, septal defects, or persistent arterial trunk. Fifty-one patients underwent surgical repair represented mainly by valvuloplasties, aortoplasty, and procedures leading to univentricular circulation. In the native hearts, 4 postnatal and 16 abortion/stillbirth cases showed discordance between gross and sonographic findings, mainly attributed to missed ventricular septal defect. Gestational age of the discordant group was significantly lower compared to the concordant group (P=.007). Conclusions: Autopsy continues to provide essential information about the morphology of congenital heart defects. However, the encountered congenital heart defects were usually complex, often surgically corrected or evaluated as a result of induced abortion or still birth. Cardiac autopsy therefore places high demands on pathologists with regards to proper gross heart assessment. It is also an invaluable part of quality control in prenatal cardiology. © 2020 Elsevier Inc.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30109 - Pathology
Result continuities
Project
—
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cardiovascular pathology
ISSN
1054-8807
e-ISSN
—
Volume of the periodical
51
Issue of the periodical within the volume
March
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
"art. no. 107309"
UT code for WoS article
000621039600007
EID of the result in the Scopus database
2-s2.0-85096478025