Magnetic resonance tractography of the lumbosacral plexus: Step-by-step

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F21%3A00080949" target="_blank" >RIV/00023001:_____/21:00080949 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/21:10428846

Result on the web

<a href="https://journals.lww.com/md-journal/Fulltext/2021/02120/Magnetic_resonance_tractography_of_the_lumbosacral.83.aspx" target="_blank" >https://journals.lww.com/md-journal/Fulltext/2021/02120/Magnetic_resonance_tractography_of_the_lumbosacral.83.aspx</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/MD.0000000000024646" target="_blank" >10.1097/MD.0000000000024646</a>

Result language

angličtina

Original language name

Magnetic resonance tractography of the lumbosacral plexus: Step-by-step

Original language description

ABSTRACT: MR tractography of the lumbosacral plexus (LSP) is challenging due to the difficulty of acquiring high quality data and accurately estimating the neuronal tracts. We proposed an algorithm for an accurate visualization and assessment of the major LSP bundles using the segmentation of the cauda equina as seed points for the initial starting area for the fiber tracking algorithm.Twenty-six healthy volunteers underwent MRI examinations on a 3T MR scanner using the phased array coils with optimized measurement protocols for diffusion-weighted images and coronal T2 weighted 3D short-term inversion recovery sampling perfection with application optimized contrast using varying flip angle evaluation sequences used for LSP fiber reconstruction and MR neurography (MRN).The fiber bundles reconstruction was optimized in terms of eliminating the muscle fibers contamination using the segmentation of cauda equina, the effects of the normalized quantitative anisotropy (NQA) and angular threshold on reconstruction of the LSP. In this study, the NQA parameter has been used for fiber tracking instead of fractional anisotropy (FA) and the regions of interest positioning was precisely adjusted bilaterally and symmetrically in each individual subject.The diffusion data were processed in individual L3-S2 nerve fibers using the generalized Q-sampling imaging algorithm. Data (mean FA, mean diffusivity, axial diffusivity and radial diffusivity, and normalized quantitative anisotropy) were statistically analyzed using the linear mixed-effects model. The MR neurography was performed in MedINRIA and post-processed using the maximum intensity projection method to demonstrate LSP tracts in multiple planes.FA values significantly decreased towards the sacral region (P &lt; .001); by contrast, mean diffusivity, axial diffusivity, radial diffusivity and NQA values significantly increased towards the sacral region (P &lt; .001).Fiber tractography of the LSP was feasible in all examined subjects and closely corresponded with the nerves visible in the maximum intensity projection images of MR neurography. Usage of NQA instead of FA in the proposed algorithm enabled better separation of muscle and nerve fibers.The presented algorithm yields a high quality reconstruction of the LSP bundles that may be helpful both in research and clinical practice. Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

<a href="/en/project/NV17-28587A" target="_blank" >NV17-28587A: MR tractography and neurography in patients with peripheral nervous system disorders</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Medicine

ISSN

0025-7974

e-ISSN

—

Volume of the periodical

100

Issue of the periodical within the volume

6

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

"art. no. e24646"

UT code for WoS article

000640700100083

EID of the result in the Scopus database

2-s2.0-85101458220