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Transplant Options for Patients With Diabetes and Advanced Kidney Disease: A Review

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F21%3A00081537" target="_blank" >RIV/00023001:_____/21:00081537 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.ajkd.org/article/S0272-6386(21)00600-4/pdf" target="_blank" >https://www.ajkd.org/article/S0272-6386(21)00600-4/pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1053/j.ajkd.2021.02.339" target="_blank" >10.1053/j.ajkd.2021.02.339</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Transplant Options for Patients With Diabetes and Advanced Kidney Disease: A Review

  • Original language description

    Optimal glycemic control in kidney transplant recipients with diabetes is associated with improved morbidity and better patient and allograft survival. Transplant options for patients with diabetes requiring insulin therapy and chronic kidney disease who are suitable candidates for kidney transplantation should include consideration of beta-cell replacement therapy: pancreas or islet transplantation. International variation related to national regulatory policies exists in offering one or both options to suitable candidates and is further affected by pancreas/islet allocation policies and transplant waiting list dynamics. The selection of appropriate candidates depends on patient age, coexistent morbidities, the timing of referral to the transplant center (predialysis versus on dialysis) and availability of living kidney donors. Therefore, early referral (estimated glomerular filtration rate &lt; 30 mL/min/1.73 m(2)) is of the utmost importance to ensure adequate time for informed decision making and thorough pretransplant evaluation. Obesity, cardiovascular disease, peripheral vascular disease, smoking, and frailty are some of the conditions that need to be addressed before acceptance on the transplant list, and ideally before dialysis becoming imminent. This review offers insights into selection of pancreas/islet transplant candidates by transplant centers and an update on posttransplant outcomes, which may have practice implications for referring nephrologists.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30217 - Urology and nephrology

Result continuities

  • Project

    <a href="/en/project/LTAUSA19073" target="_blank" >LTAUSA19073: Evidence based state-of-the-art data evaluation of pancreatic islet transplant prog1ram: Contribution of the Czech Republic data to CITR, Collaborative Islet Transplant Registry</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    American journal of kidney diseases

  • ISSN

    0272-6386

  • e-ISSN

  • Volume of the periodical

    78

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    11

  • Pages from-to

    418-428

  • UT code for WoS article

    000686900900015

  • EID of the result in the Scopus database

    2-s2.0-85104440298