Renal transplantation in a unique porcine model : step-by-step
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F22%3A00083999" target="_blank" >RIV/00023001:_____/22:00083999 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/22:10466171 RIV/00216208:11110/22:10466171
Result on the web
<a href="http://www.ijotm.com/ojs/index.php/IJOTM/article/view/1017" target="_blank" >http://www.ijotm.com/ojs/index.php/IJOTM/article/view/1017</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Renal transplantation in a unique porcine model : step-by-step
Original language description
Background: Kidney transplantation is the most common solid organ transplantation. The aim of our research is to describe technical and surgical aspects of a porcine model of heterotopic kidney allotransplantation, using up-to-date techniques, utilized nowadays during human kidney transplantation. Methods: We performed a total of 20 heterotopic kidney transplantations on a porcine animal model. The manipulation time, cold ischemia time and surgery time were measured and analyzed over time. Results: Over the course of the experiment manipulation time decreased by 32% from 28min to 19min, cold ischemia time decreased by 33% from 46min to 31min, and surgery time decreased by 28% from 180min to 130min. All animals had successful reperfusion of the grafts. We witnessed urination of all grafts before performing the ureteral anastomosis. Three grafts had an early graft failure due to an early arterial thrombosis; in the first two cases, the grafts had their artery anastomosed onto a thin external iliac artery, the third thrombosis occurred on a graft with complex arterial anatomy with implanted pole artery. Conclusion: Our experimental model demonstrated that a pig laboratory model is a useful and valuable tool for surgical training. It can help to shorten the operation times and lower the complication rates. This specific model can also be extended to serve not only as a simple training tool for surgical techniques. Considering pig to human similarities in physiology, biochemistry, and immunology, it can also be used as a short- or long-term model in kidney transplantation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30213 - Transplantation
Result continuities
Project
<a href="/en/project/NV16-34134A" target="_blank" >NV16-34134A: System for Continuous Early Postoperative Monitoring of Kidney Graft Blood Perfusion</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International journal of organ transplantation medicine
ISSN
2008-6490
e-ISSN
2008-6482
Volume of the periodical
13
Issue of the periodical within the volume
4
Country of publishing house
IR - IRAN, ISLAMIC REPUBLIC OF
Number of pages
11
Pages from-to
30-40
UT code for WoS article
001024884600002
EID of the result in the Scopus database
2-s2.0-85165441813