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Morphological aspects of small-duct cholangiopathies : a minireview

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F23%3A00083956" target="_blank" >RIV/00023001:_____/23:00083956 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/23:43925477 RIV/00064173:_____/23:43925477 RIV/00064190:_____/23:10001158

  • Result on the web

    <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190694/pdf/WJH-15-538.pdf" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190694/pdf/WJH-15-538.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4254/wjh.v15.i4.538" target="_blank" >10.4254/wjh.v15.i4.538</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Morphological aspects of small-duct cholangiopathies : a minireview

  • Original language description

    The biliary system consists of intrahepatic and extrahepatic bile ducts lined by biliary epithelial cells (cholangiocytes). Bile ducts and cholangiocytes are affected by a variety of disorders called cholangiopathies, which differ in aetiology, pathogenesis, and morphology. Classification of cholangiopathies is complex and reflects pathogenic mechanisms (immune-mediated, genetic, drug- and toxin-induced, ischaemic, infectious, neoplastic), predominant morphological patterns of biliary injury (suppurative and non-suppurative cholangitis, cholangiopathy), and specific segments of the biliary tree affected by the disease process. While the involvement of large extrahepatic and intrahepatic bile ducts is typically visualised using radiology imaging, histopathological examination of liver tissue obtained by percutaneous liver biopsy still plays an important role in the diagnosis of cholangiopathies affecting the small intrahepatic bile ducts. To increase the diagnostic yield of a liver biopsy and determine the optimal therapeutic approach, the referring clinician is tasked with interpreting the results of histopathological examination. This requires knowledge and understanding of basic morphological patterns of hepatobiliary injury and an ability to correlate microscopic findings with results obtained by imaging and laboratory methods. This minireview describes the morphological aspects of small-duct cholangiopathies pertaining to the diagnostic process.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30219 - Gastroenterology and hepatology

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    World journal of hepatology

  • ISSN

    1948-5182

  • e-ISSN

    1948-5182

  • Volume of the periodical

    15

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    16

  • Pages from-to

    538-553

  • UT code for WoS article

    000991654900007

  • EID of the result in the Scopus database

    2-s2.0-85159035877