Longitudinal trends in severe dyslipidemia in the Czech population : the Czech MONICA and Czech Post-MONICA study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F23%3A00084126" target="_blank" >RIV/00023001:_____/23:00084126 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11140/23:10467715 RIV/00064190:_____/23:10001174 RIV/00216208:11110/23:10467715

Result on the web

<a href="https://www.mdpi.com/2308-3425/10/8/328" target="_blank" >https://www.mdpi.com/2308-3425/10/8/328</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/jcdd10080328" target="_blank" >10.3390/jcdd10080328</a>

Result language

angličtina

Original language name

Longitudinal trends in severe dyslipidemia in the Czech population : the Czech MONICA and Czech Post-MONICA study

Original language description

Background: Severe hypercholesterolemia is associated with an increase in the risk of developing atherosclerotic cardiovascular disease. The aim of this analysis was to assess longitudinal trends in severe dyslipidemia (defined as total cholesterol &gt; 8 mmol/L or LDL-cholesterol &gt; 5 mmol/L) in a representative population sample of the Czech Republic and to analyze the longitudinal trends in the basic characteristics of individuals with severe dyslipidemia. Methods: Seven independent cross-sectional surveys were organized in the Czech Republic to screen for major cardiovascular risk factors (from 1985 to 2015-2018). A total of 20,443 randomly selected individuals aged 25-64 years were examined. Results: The overall prevalence of severe dyslipidemia was 6.6%, with a significant downward trend from the fifth survey onwards (2000/2001). Over the study period of 30+ years, the individuals with severe dyslipidemia became older, increased in BMI, and did not change their smoking habits. Total cholesterol and non-HDL-cholesterol decreased significantly in both sexes throughout the duration of the study. Conclusions: Despite a significant improvement in lipids in the Czech Republic from 1985, substantially contributing to the decline in cardiovascular mortality, the number of individuals with severe dyslipidemia remained high, and in most cases, they were newly detected during our screening examinations and were thus untreated.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

<a href="/en/project/NV15-27109A" target="_blank" >NV15-27109A: Longitudinal trends in major cardiovascular risk factors and their predictive value in a population random sample, Czech post-MONICA study</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of cardiovascular development and disease

ISSN

2308-3425

e-ISSN

2308-3425

Volume of the periodical

10

Issue of the periodical within the volume

8

Country of publishing house

CH - SWITZERLAND

Number of pages

9

Pages from-to

"art. no. 328"

UT code for WoS article

001056814500001

EID of the result in the Scopus database

2-s2.0-85169141012