Update on anticoagulation strategies in patients with ECMO-A narrative review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F23%3A00084249" target="_blank" >RIV/00023001:_____/23:00084249 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/23:10469512 RIV/00064165:_____/23:10469512
Result on the web
<a href="https://www.mdpi.com/2077-0383/12/18/6067" target="_blank" >https://www.mdpi.com/2077-0383/12/18/6067</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/jcm12186067" target="_blank" >10.3390/jcm12186067</a>
Alternative languages
Result language
angličtina
Original language name
Update on anticoagulation strategies in patients with ECMO-A narrative review
Original language description
The use of extracorporeal membrane oxygenation (ECMO) has recently increased exponentially. ECMO has become the preferred mode of organ support in refractory respiratory or circulatory failure. The fragile balance of haemostasis physiology is massively altered by the patient's critical condition and specifically the aetiology of the underlying disease. Furthermore, an application of ECMO conveys another disturbance of haemostasis due to blood-circuit interaction and the presence of an oxygenator. The purpose of this review is to summarise current knowledge on the anticoagulation management in patients undergoing ECMO therapy. The unfractionated heparin modality with monitoring of activated partial thromboplastin tests is considered to be a gold standard for anticoagulation in this specific subgroup of intensive care patients. However, alternative modalities with other agents are comprehensively discussed. Furthermore, other ways of monitoring can represent the actual state of coagulation in a more complex fashion, such as thromboelastometric/graphic methods, and might become more frequent. In conclusion, the coagulation system of patients with ECMO is altered by multiple variables, and there is a significant lack of evidence in this area. Therefore, a highly individualised approach is the best solution today.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of clinical medicine
ISSN
2077-0383
e-ISSN
2077-0383
Volume of the periodical
12
Issue of the periodical within the volume
18
Country of publishing house
CH - SWITZERLAND
Number of pages
15
Pages from-to
"art. no. 6067"
UT code for WoS article
001073640700001
EID of the result in the Scopus database
2-s2.0-85172790358