Accuracy and feasibility of real-time continuous glucose monitoring in critically Ill patients after abdominal surgery and solid organ transplantation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F24%3A00084941" target="_blank" >RIV/00023001:_____/24:00084941 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/24:10478288 RIV/00216208:11120/24:43926721

Result on the web

<a href="https://diabetesjournals.org/care/article/47/6/956/154297/Accuracy-and-Feasibility-of-Real-time-Continuous" target="_blank" >https://diabetesjournals.org/care/article/47/6/956/154297/Accuracy-and-Feasibility-of-Real-time-Continuous</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2337/dc23-1663" target="_blank" >10.2337/dc23-1663</a>

Result language

angličtina

Original language name

Accuracy and feasibility of real-time continuous glucose monitoring in critically Ill patients after abdominal surgery and solid organ transplantation

Original language description

OBJECTIVE Glycemia management in critical care is posing a challenge in frequent measuring and adequate insulin dose adjustment. In recent years, continuous glucose measurement has gained accuracy and reliability in outpatient and inpatient settings. The aim of this study was to assess the feasibility and accuracy of real-time continuous glucose monitoring (CGM) in ICU patients after major abdominal surgery. RESEARCH DESIGN AND METHODS We included patients undergoing pancreatic surgery and solid organ transplantation (liver, pancreas, islets of Langerhans, kidney) requiring an ICU stay after surgery. We used a Dexcom G6 sensor, placed in the infraclavicular region, for real-time CGM. Arterial blood glucose measured by the amperometric principle (ABL 800; Radiometer, Copenhagen, Denmark) served as a reference value and for calibration. Blood glucose was also routinely monitored by a StatStrip bedside glucose meter. Sensor accuracy was assessed by mean absolute relative difference (MARD), bias, modified Bland-Altman plot, and surveillance error grid for paired samples of glucose values from CGM and acid-base analyzer (ABL). RESULTS We analyzed data from 61 patients and obtained 1,546 paired glucose values from CGM and ABL. Active sensor use was 95.1%. MARD was 9.4%, relative bias was 1.4%, and 92.8% of values fell in zone A, 6.1% fell in zone B, and 1.2% fell in zone C of the surveillance error grid. Median time in range was 78%, with minimum (&lt;1%) time spent in hypoglycemia. StatStrip glucose meter MARD compared with ABL was 5.8%. CONCLUSIONS Our study shows clinically applicable accuracy and reliability of Dexcom G6 CGM in postoperative ICU patients and a feasible alternative sensor placement site.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30202 - Endocrinology and metabolism (including diabetes, hormones)

Project

<a href="/en/project/LX22NPO5104" target="_blank" >LX22NPO5104: National Institute for Research of Metabolic and Cardiovascular Diseases</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Diabetes care

ISSN

0149-5992

e-ISSN

1935-5548

Volume of the periodical

47

Issue of the periodical within the volume

6

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

956-963

UT code for WoS article

001297160700015

EID of the result in the Scopus database

2-s2.0-85194013767