The use of autologous cell therapy in diabetic patients with chronic limb-threatening ischemia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F24%3A00085052" target="_blank" >RIV/00023001:_____/24:00085052 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/24:10485919 RIV/00216208:11130/24:10485919
Result on the web
<a href="https://www.mdpi.com/1422-0067/25/18/10184" target="_blank" >https://www.mdpi.com/1422-0067/25/18/10184</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms251810184" target="_blank" >10.3390/ijms251810184</a>
Alternative languages
Result language
angličtina
Original language name
The use of autologous cell therapy in diabetic patients with chronic limb-threatening ischemia
Original language description
Autologous cell therapy (ACT) is primarily used in diabetic patients with chronic limb-threatening ischemia (CLTI) who are not candidates for standard revascularization. According to current research, this therapy has been shown in some studies to be effective in improving ischemia parameters, decreasing the major amputation rate, and in foot ulcer healing. This review critically evaluates the efficacy of ACT in patients with no-option CLTI, discusses the use of mononuclear and mesenchymal stem cells, and compares the route of delivery of ACT. In addition to ACT, we also describe the use of new revascularization strategies, e.g., nanodiscs, microbeads, and epigenetics, that could enhance the therapeutic effect. The main aim is to summarize new findings on subcellular and molecular levels with the clinical aspects of ACT.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
<a href="/en/project/LX22NPO5104" target="_blank" >LX22NPO5104: National Institute for Research of Metabolic and Cardiovascular Diseases</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International journal of molecular sciences
ISSN
1661-6596
e-ISSN
1422-0067
Volume of the periodical
25
Issue of the periodical within the volume
18
Country of publishing house
CH - SWITZERLAND
Number of pages
16
Pages from-to
"art. no. 10184"
UT code for WoS article
001324055000001
EID of the result in the Scopus database
2-s2.0-85205236317