Safety and efficacy of a temperature-controlled ablation system for ventricular tachycardia: Results from the TRAC-VT study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F25%3A00085793" target="_blank" >RIV/00023001:_____/25:00085793 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007/s10840-025-01995-z" target="_blank" >https://link.springer.com/article/10.1007/s10840-025-01995-z</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10840-025-01995-z" target="_blank" >10.1007/s10840-025-01995-z</a>
Alternative languages
Result language
angličtina
Original language name
Safety and efficacy of a temperature-controlled ablation system for ventricular tachycardia: Results from the TRAC-VT study
Original language description
BackgroundCatheter ablation using radiofrequency (RF) energy is an established treatment for ventricular tachycardia (VT). Tissue temperature is a key determinant of successful lesion creation, and yet, it is difficult to measure during conventional RF ablation because of the cooling effect of high-flow rate saline irrigation. The TRAC-VT study evaluated the safety and efficacy of a novel irrigated RF ablation system modulating power based on real-time tissue temperature.MethodsPatients with sustained monomorphic VT and structural heart disease (SHD) were enrolled. Catheter ablation was performed in temperature-control mode (irrigation 8 ml/min, temperature set-points 55 or 60 degrees C, and power output <= 50 W), with RF applications for <= 45 s. The primary safety endpoint was a composite of cardiovascular-specific serious procedure-related adverse events within 30 days post-ablation. The primary effectiveness endpoint was acute success (i.e., non-inducibility of all clinically relevant VTs).ResultsThirty-eight patients were enrolled with monomorphic VT (age 68 +/- 12 years and 84% male), with an average of 1.7 +/- 1.2 VTs targeted per patient. In total, 41 +/- 23 RF applications per patient were delivered. Acute procedural success was 100% (95% CI, 91-100%). No primary safety endpoints were observed. Six-month follow-up was completed in 92% of patients with 81% (95% CI, 65-91%) freedom from sustained or treated VT. A repeat ablation was performed in three patients.ConclusionsAblation of VT in SHD, using a temperature-controlled irrigated RF catheter, was safe and effective with a low rate of VT recurrence at 6 months.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of interventional cardiac electrophysiology: an international journal of arrhythmias and pacing
ISSN
1383-875X
e-ISSN
1572-8595
Volume of the periodical
68
Issue of the periodical within the volume
6
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
8
Pages from-to
"1217–1224"
UT code for WoS article
001410565500001
EID of the result in the Scopus database
2-s2.0-85217397542