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The impact of pathological conditions on carbon and nitrogen isotopic values in the bone collagen of individuals with known biographic data and medical history

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023272%3A_____%2F21%3A10135152" target="_blank" >RIV/00023272:_____/21:10135152 - isvavai.cz</a>

  • Alternative codes found

    RIV/60077344:_____/21:00544007 RIV/00216208:11110/21:10439314 RIV/00216208:11310/21:10439314

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1002/oa.3022" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/oa.3022</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/oa.3022" target="_blank" >10.1002/oa.3022</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The impact of pathological conditions on carbon and nitrogen isotopic values in the bone collagen of individuals with known biographic data and medical history

  • Original language description

    This study aimed to refine our understanding of the extent to which chronic diseases with and without skeletal manifestation affect the isotopic values in bone collagen. Carbon and nitrogen isotopic values were measured in the ribs and femurs of 65 individuals from a documented skeletal collection (19th-21st centuries, Czech Republic). Statistically significant differences in both carbon and nitrogen isotopic values were found between particular families. There was a notable effect of the year of death on nitrogen isotopic values in ribs. Neither the presence of chronic disease in general nor the presence of carcinoma, age-related physical debility, or tuberculosis had a significant impact on isotopic values. Cases of cancer with skeletal metastases however showed an increase of 1 parts per thousand-1.5 parts per thousand in nitrogen isotopic values in (i) metastasis tissue, (ii) the healthy areas of bone affected by the metastasis, and (iii) the healthy rib bone. The results demonstrate that distinct dietary habits in particular families are the main driving force affecting the isotopic values in the sampled individuals. A minor but notable temporal shift in the nitrogen isotopic values of ribs may be linked to environmental and/or societal changes during the studied period. The observed increase in the nitrogen isotopic values of individuals with bone cancer metastases is in accordance with the state of cachexia and negative nitrogen balance. Despite the low number of cases, this result urges caution, as isotopic changes to the observed degree may significantly affect the dietary interpretation of the isotopic data.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10620 - Other biological topics

Result continuities

  • Project

    <a href="/en/project/GA19-13265S" target="_blank" >GA19-13265S: Refining the dietary reconstruction of past populations at the example of medieval Moravia</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Osteoarchaeology

  • ISSN

    1047-482X

  • e-ISSN

  • Volume of the periodical

    31

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    20

  • Pages from-to

    1105-1124

  • UT code for WoS article

    000670611200001

  • EID of the result in the Scopus database