Evaluation of Cell-Free Urine microRNAs Expression for the Use in Diagnosis of Ovarian and Endometrial Cancers. A Pilot Study.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023698%3A_____%2F15%3A%230000176" target="_blank" >RIV/00023698:_____/15:#0000176 - isvavai.cz</a>
Alternative codes found
RIV/67985939:_____/15:00447519 RIV/68378050:_____/15:00456692 RIV/00216224:14110/15:00083502 RIV/00216208:11110/15:10297883 and 3 more
Result on the web
<a href="http://dx.doi.org/10.1007/s12253-015-9914-y" target="_blank" >http://dx.doi.org/10.1007/s12253-015-9914-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12253-015-9914-y" target="_blank" >10.1007/s12253-015-9914-y</a>
Alternative languages
Result language
angličtina
Original language name
Evaluation of Cell-Free Urine microRNAs Expression for the Use in Diagnosis of Ovarian and Endometrial Cancers. A Pilot Study.
Original language description
Among gynaecological cancers, epithelial ovarian cancers are the most deadly cancers while endometrial cancers are the most common diseases. Efforts to establish relevant novel diagnostic, screening and prognostic markers are aimed to help reduce the high level of mortality, chemoresistance and recurrence, particularly in ovarian cancer. MicroRNAs, the class of post-transcriptional regulators, have emerged as the promising diagnostic and prognostic markers associated with various diseased states recently. Urine has been shown as the source of microRNAs several years ago; however, there has been lack of information on urine microRNA expression in ovarian and endometrial cancers till now. In this pilot study, we examined the expression of candidate cell-free urine microRNAs in ovarian cancer and endometrial cancer patients using quantitative real-time PCR. We compared the expression between pre- and post-surgery ovarian cancer samples, and between patients with ovarian and endometrial cancers and healthy controls, within three types of experiments.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pathology and Oncology Research
ISSN
1219-4956
e-ISSN
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Volume of the periodical
21
Issue of the periodical within the volume
4
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
9
Pages from-to
1027-1035
UT code for WoS article
00360385400023
EID of the result in the Scopus database
2-s2.0-84940448066