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Evaluation of Cell-Free Urine microRNAs Expression for the Use in Diagnosis of Ovarian and Endometrial Cancers. A Pilot Study.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023698%3A_____%2F15%3A%230000176" target="_blank" >RIV/00023698:_____/15:#0000176 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985939:_____/15:00447519 RIV/68378050:_____/15:00456692 RIV/00216224:14110/15:00083502 RIV/00216208:11110/15:10297883 and 3 more

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s12253-015-9914-y" target="_blank" >http://dx.doi.org/10.1007/s12253-015-9914-y</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s12253-015-9914-y" target="_blank" >10.1007/s12253-015-9914-y</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Evaluation of Cell-Free Urine microRNAs Expression for the Use in Diagnosis of Ovarian and Endometrial Cancers. A Pilot Study.

  • Original language description

    Among gynaecological cancers, epithelial ovarian cancers are the most deadly cancers while endometrial cancers are the most common diseases. Efforts to establish relevant novel diagnostic, screening and prognostic markers are aimed to help reduce the high level of mortality, chemoresistance and recurrence, particularly in ovarian cancer. MicroRNAs, the class of post-transcriptional regulators, have emerged as the promising diagnostic and prognostic markers associated with various diseased states recently. Urine has been shown as the source of microRNAs several years ago; however, there has been lack of information on urine microRNA expression in ovarian and endometrial cancers till now. In this pilot study, we examined the expression of candidate cell-free urine microRNAs in ovarian cancer and endometrial cancer patients using quantitative real-time PCR. We compared the expression between pre- and post-surgery ovarian cancer samples, and between patients with ovarian and endometrial cancers and healthy controls, within three types of experiments.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Pathology and Oncology Research

  • ISSN

    1219-4956

  • e-ISSN

  • Volume of the periodical

    21

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    9

  • Pages from-to

    1027-1035

  • UT code for WoS article

    00360385400023

  • EID of the result in the Scopus database

    2-s2.0-84940448066