Preoperative application of the Enzian classification for endometriosis (The cEnzian Study): A prospective international multicenter study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023698%3A_____%2F22%3AN0000006" target="_blank" >RIV/00023698:_____/22:N0000006 - isvavai.cz</a>
Result on the web
<a href="https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.17235" target="_blank" >https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.17235</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/1471-0528.17235" target="_blank" >10.1111/1471-0528.17235</a>
Alternative languages
Result language
angličtina
Original language name
Preoperative application of the Enzian classification for endometriosis (The cEnzian Study): A prospective international multicenter study
Original language description
Objective To assess the diagnostic performance of preoperative application of the Enzian classification (cEnzian) using surgical findings as reference standard. Design A prospective international non-interventional study. Setting Twelve endometriosis centres in four European countries (Austria, Germany, Switzerland and Czech Republic). Population 1062 women with endometriosis surgery. Methods Extent of endometriosis was preoperatively classified using the cEnzian classification based on gynaecological examination and/or transvaginal ultrasound (TVS) and/or magnetic resonance imaging (MRI). After subsequent surgery, the surgeon classified the intraoperative findings using the Enzian classification. Main outcome measures Sensitivity, specificity, PPV, NPV, LR+, LR- and accuracy were calculated. Conditional frequencies of intraoperative Enzian codings and the corresponding 95% confidence intervals were computed for each preoperative coding and visualised in plots. Results Although overall consistency of cEnzian and Enzian was poor (35.14%, 95% confidence interval 32.26-38.03), high specificities and negative predictive values (NPVs) of the cEnzian compartments could be demonstrated. Looking at the individual parts of the Enzian classification, the poorest diagnostic performance was detected for compartment B and the highest PPVs were found for category 3 lesions (>3 cm), independent of the compartment. Conclusions Using the Enzian classification in a non-invasive setting is a useful tool providing us with an 'at a glance' summary of the diagnostic workup regarding deep endometriosis with high specificities and NPVs. An attempt to merge the two new endometriosis classification systems (#Enzian and AAGL 2021) seems reasonable taking into consideration the respective advantages of each other.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30214 - Obstetrics and gynaecology
Result continuities
Project
—
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
ISSN
1470-0328
e-ISSN
1471-0528
Volume of the periodical
129
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
2052-2061
UT code for WoS article
000805611200001
EID of the result in the Scopus database
2-s2.0-85131177242