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Comparison of Cross-Sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023698%3A_____%2F24%3AN0000020" target="_blank" >RIV/00023698:_____/24:N0000020 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/24:43926709 RIV/00064173:_____/24:43926709

  • Result on the web

    <a href="https://pubmed.ncbi.nlm.nih.gov/38376549/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/38376549/</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00192-024-05733-3" target="_blank" >10.1007/s00192-024-05733-3</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Comparison of Cross-Sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women

  • Original language description

    Introduction and HypothesisThe main risk factor for pelvic floor disorders is vaginal delivery, which may cause levator ani muscle (LAM) injury and denervation. LAM includes pubovisceral muscle (PVM, pubococcygeus), puborectalis muscle (PRM), and iliococcygeus muscle. We hypothesize that primiparous women with low pelvic floor muscle contraction have a reduced PVM cross-sectional area (CSA) compared to nulliparous women.Methods (Sample Size and Statistical Approaches)This single-centre prospective observational study compared healthy nulliparous (n = 40) to primiparous (n = 40) women after vaginal delivery without LAM avulsion and Oxford score <= 3. Demographics, questionnaires (ICIQ-UI-SF, OAB-Q-SF, PISQ-12), POP-Q, Oxford score, ultrasound measurements (minimal anteroposterior and lateral diameters, hiatal area, PRM thickness, levator-urethra gap) and magnetic resonance imaging (MRI)-PVM CSA were evaluated. Normality was tested, and an appropriate test was used to compare the groups. Power calculation suggested 40 participants per group.ResultsThe primiparous group was older, had a higher BMI, and their hiatal area on ultrasound at contraction was larger compared to the nulliparous group. The CSA of the left-sided PVM (1.15 +/- 0.50 cm2) was larger compared to the right side (1.03 +/- 0.50 cm2), p = 0.02 in nulliparous women. The PVM CSA of primiparous women with low Oxford score was reduced compared to nulliparous (0.87 +/- 0.30 versus 1.09 +/- 0.50 cm2, p = 0.006). The intra-rater reliability for PVM CSA had an ICC of 0.90 and inter-rater ICC of 0.77.ConclusionsPrimiparous women after vaginal delivery with low pelvic floor contraction force had reduced PVM CSA on MRI images compared to nulliparous women.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30214 - Obstetrics and gynaecology

Result continuities

  • Project

    <a href="/en/project/EF19_073%2F0016935" target="_blank" >EF19_073/0016935: Grant schemes at Charles University</a><br>

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    INTERNATIONAL UROGYNECOLOGY JOURNAL

  • ISSN

    0937-3462

  • e-ISSN

    1433-3023

  • Volume of the periodical

    35

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    841-848

  • UT code for WoS article

    001171727700003

  • EID of the result in the Scopus database

    2-s2.0-85185330523