Different risk of acute feto-fetal transfusion in basic clinical subtypes of monochorionic twins
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023698%3A_____%2F25%3AN0000006" target="_blank" >RIV/00023698:_____/25:N0000006 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/25:43928739 RIV/00216208:11140/25:10501030
Result on the web
<a href="https://doi.org/10.1016/j.placenta.2025.07.093" target="_blank" >https://doi.org/10.1016/j.placenta.2025.07.093</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.placenta.2025.07.093" target="_blank" >10.1016/j.placenta.2025.07.093</a>
Alternative languages
Result language
angličtina
Original language name
Different risk of acute feto-fetal transfusion in basic clinical subtypes of monochorionic twins
Original language description
Analysis of the potential risk of acute feto-fetal transfusion (aFFT) in different clinical types of monochorionic twins using an in vitro placental simulation model. The prospective study analyzed 157 fresh MC placentas from 2014 to 2020, excluding those with intrauterine intervention. A specially designed protocol was used for their preparation and analysis. The study included 108 placentas with an uncomplicated course, 31 cases of selective fetal growth restriction (sFGR), and 18 cases of twin-to-twin transfusion syndrome (TTTS). The number and types of anastomoses, umbilical cord insertion distances (UCID), and placental areas for each fetus were statistically analyzed. The primary objective was to assess differences in aFFT among various MC twin subtypes. The secondary objectives were to identify risk factors associated with the development of aFFT. 76/157 (48.4 %) cases of aFFT were confirmed, with an average transfusion time of 1 mL in 50 s (8-240 s). The occurrence of aFFT in uncomplicated, sFGR, and TTTS placentas was 62,5 %, 50,9 %, and 5,9 %, respectively (p < 0.001). The representation of AA anastomoses was significantly higher in the sFGR and uncomplicated groups compared to TTTS (84.4 % and 80.6 % vs. 11.8 %; p < 0.001). Besides the presence of AA anastomosis, the main independent risk factor for the development of aFFT is its diameter (p < 0.001). The potential risk of aFFT differs significantly among individual clinical subtypes of MC twins, depending on the presence and size of AA anastomosis.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30214 - Obstetrics and gynaecology
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLACENTA
ISSN
0143-4004
e-ISSN
1532-3102
Volume of the periodical
170
Issue of the periodical within the volume
October
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
36-41
UT code for WoS article
001550914900001
EID of the result in the Scopus database
2-s2.0-105012847543