Treat-to-target strategy for knee osteoarthritis. International technical expert panel consensus and good clinical practice statements.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023728%3A_____%2F19%3AN0000080" target="_blank" >RIV/00023728:_____/19:N0000080 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1177/1759720X19893800" target="_blank" >https://doi.org/10.1177/1759720X19893800</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/1759720X19893800" target="_blank" >10.1177/1759720X19893800</a>

Result language

angličtina

Original language name

Treat-to-target strategy for knee osteoarthritis. International technical expert panel consensus and good clinical practice statements.

Original language description

In this work, we aimed to establish a clinical target in the management of knee osteoarthritis (KOA) and to propose good clinical practice (GCP) statements for carrying out a treat-to-target strategy. Methods: A steering committee of seven experts had formulated a provisional set of recommendations that were exposed for discussion and modification to a technical expert panel (TEP) of 25 multidisciplinary experts from Europe, North America, South America and Asia. The level of evidence and strength of each recommendation was discussed. The TEP formulated overarching principles and GCP statements based on the level of agreement for each item with a vote using a 10-point numerical scale. Results: Two overarching principles and 10 GCP statements were formulated by the TEP. These GCP statements suggest: treatment should achieve clinical improvement bringing the patient to the Patient Acceptable Symptom State (PASS); pharmacological and nonpharmacological treatment should begin as early as possible, with an early diagnosis of symptomatic KOA; the patient should be evaluated every 3-6 months; risk factors of KOA progression should be identified and managed with patients at the beginning of the treatment and monitored regularly; treatment should be adapted according to patient phenotype and disease severity; healthy lifestyle must be promoted and monitored. The level of agreement average ranged from 8.7 to 9.6 on scale. Conclusions: The proposed overarching principles and GCP statements have the aim of involving patients, general practitioners and multidisciplinary specialists in sharing a therapeutic treat-to-target strategy for KOA management based on the best evidence and expert opinions

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30226 - Rheumatology

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE

ISSN

1759-720X

e-ISSN

1759-7218

Volume of the periodical

11

Issue of the periodical within the volume

Art. Nr.1759720X19893800

Country of publishing house

GB - UNITED KINGDOM

Number of pages

15

Pages from-to

1-15

UT code for WoS article

000503793100001

EID of the result in the Scopus database

2-s2.0-85077147221