Differential gene expression of bone marrow CD34+ cells in early and advanced myelodysplastic syndrome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F09%3A00008185" target="_blank" >RIV/00023736:_____/09:00008185 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Differential gene expression of bone marrow CD34+ cells in early and advanced myelodysplastic syndrome

Original language description

Myelodysplastic syndrome (MDS) is a hematopoietic stem cell disorder characterized by ineffective hematopoiesis and dysplasia in one or more blood cell lines. Our study identified several differentially expressed genes using microarrays between early andadvanced MDS patients. Expression levels of ADAM8, BIRC5 and MPL were validated in additional set of 29 patients using qRT-PCR. Their specific expression pattern was confirmed: higher expression of ADAM8 and MPL and lower expression of BIRC5 in advancedMDS compared to early MDS patients.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

<a href="/en/project/NR9235" target="_blank" >NR9235: INVESTIGATION OF GENE EXPRESSION PROFILING IN PATIENTS WITH MYELODYSPLASTIC SYNDROME</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neoplasma

ISSN

0028-2685

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

4

Country of publishing house

SK - SLOVAKIA

Number of pages

8

Pages from-to

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UT code for WoS article

000271991100009

EID of the result in the Scopus database

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