Altered HLA class I profile associated with type A/D nucleophosmin mutation points to possible anti-nucleophosmin immune response in acute myeloid leukemia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F15%3A00011321" target="_blank" >RIV/00023736:_____/15:00011321 - isvavai.cz</a>
Result on the web
<a href="http://www.scopus.com/inward/record.url?eid=2-s2.0-84930639890&partnerID=40&md5=9c2c08b20e66d3f6bebc72575b2f4c5d" target="_blank" >http://www.scopus.com/inward/record.url?eid=2-s2.0-84930639890&partnerID=40&md5=9c2c08b20e66d3f6bebc72575b2f4c5d</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0127637" target="_blank" >10.1371/journal.pone.0127637</a>
Alternative languages
Result language
angličtina
Original language name
Altered HLA class I profile associated with type A/D nucleophosmin mutation points to possible anti-nucleophosmin immune response in acute myeloid leukemia
Original language description
Nucleophosmin 1 (NPM1) mutations are frequently found in patients with acute myeloid leukemia (AML) and the newly generated sequences were suggested to induce immune response contributing to the relatively favorable outcome of patients in this AML subset. Our analysis suggests that individuals expressing specific HLA allelic groups are disposed to develop an efficient anti-AML immune response thanks to aberrant cytoplasmic localization of the mutated NPM protein.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLoS one
ISSN
1932-6203
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
"art. no. e0127637"
UT code for WoS article
000354921400128
EID of the result in the Scopus database
2-s2.0-84930639890