Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R): a study of the International Working Group for Prognosis in Myelodysplasia (IWG-PM)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F15%3A00011358" target="_blank" >RIV/00023736:_____/15:00011358 - isvavai.cz</a>

Result on the web

<a href="http://www.scopus.com/inward/record.url?eid=2-s2.0-84937024459&partnerID=40&md5=1113719e4a4f2bf23e4ff0c03c9daede" target="_blank" >http://www.scopus.com/inward/record.url?eid=2-s2.0-84937024459&partnerID=40&md5=1113719e4a4f2bf23e4ff0c03c9daede</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/leu.2015.55" target="_blank" >10.1038/leu.2015.55</a>

Result language

angličtina

Original language name

Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R): a study of the International Working Group for Prognosis in Myelodysplasia (IWG-PM)

Original language description

We refined the World Health Organization (WHO)-classification-based Prognostic Scoring System (WPSS) by determining the impact of the newer clinical and cytogenetic features, and we compared its prognostic power to that of the revised International Prognostic Scoring System (IPSS-R). A population of 5326 untreated MDS was considered. We analyzed single WPSS parameters and confirmed that the WHO classification and severe anemia provide important prognostic information in MDS. A strong correlation was found between the WPSS including the new cytogenetic risk stratification and WPSS adopting original criteria. We then compared WPSS with the IPSS-R prognostic system, both systems well represent the prognostic risk of MDS patients defined by WHO morphologic criteria. This study provides relevant information for the implementation of risk-adapted strategies in MDS.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

—

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Leukemia

ISSN

0887-6924

e-ISSN

—

Volume of the periodical

29

Issue of the periodical within the volume

7

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

1502-1513

UT code for WoS article

000357623100010

EID of the result in the Scopus database

2-s2.0-84937024459